A 56-year-old diabetic man with a foot infection on antibiotic treatment experienced a headache and visual change. A 56-year-old diabetic man with a foot infection on antibiotic treatment experienced a headache and visual change. Baseline blood pressure was 191/88 mm Hg, and blood pressure at toxicity was 215/115 mm Hg.A–B, Brain MR imaging (FLAIR sequence) obtained at toxicity demonstrates vasogenic edema in the occipital lobes (open arrows) and parietal region (curved arrows) bilaterally as well as involvement in the cerebellum bilaterally (not shown). This is representative and typical of the dominant parietal-occipital pattern. CSF hyperintensity is noted, likely related to ongoing oxygen administration. W.S. Bartynski, and J.F. Boardman AJNR Am J Neuroradiol 2007;28:1320-1327 ©2007 by American Society of Neuroradiology