M.S. Schaefer, T.A. Treschan, J. Gauch, M. Neukirchen, P. Kienbaum

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Measurement of static and dynamic compliance during mechanical ventilation. A tidal volume is delivered, causing a peak in airway pressure; dynamic compliance.

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Presentation transcript:

Influence of xenon on pulmonary mechanics and lung aeration in patients with healthy lungs M.S. Schaefer, T.A. Treschan, J. Gauch, M. Neukirchen, P. Kienbaum British Journal of Anaesthesia Volume 120, Issue 6, Pages 1394-1400 (June 2018) DOI: 10.1016/j.bja.2018.02.064 Copyright © 2018 British Journal of Anaesthesia Terms and Conditions

Fig. 1 Transpulmonary pressure during propofol and subsequent xenon-based anaesthesia in all patients, and separate for subgroups of patients with normal weight (BMI <25 kg m−2) and obese patients (BMI>30 kg m−2). n.s.: not significant. British Journal of Anaesthesia 2018 120, 1394-1400DOI: (10.1016/j.bja.2018.02.064) Copyright © 2018 British Journal of Anaesthesia Terms and Conditions

Fig. 2 Airway resistance (RAW), dynamic (Cdyn), and static (Cstat) compliance of the respiratory system during propofol and subsequent xenon-based anaesthesia. *** P<0.001; n.s.: not significant. British Journal of Anaesthesia 2018 120, 1394-1400DOI: (10.1016/j.bja.2018.02.064) Copyright © 2018 British Journal of Anaesthesia Terms and Conditions

Fig. 3 Distribution of tidal volume in the anterior-posterior direction, as quantified by the centre of ventilation index before induction of anaesthesia, during initial propofol, and subsequent xenon-based anaesthesia. BMI (kg m−2). ***P<0.001; ** P<0.01; *P<0.05; n.s.: not significant. British Journal of Anaesthesia 2018 120, 1394-1400DOI: (10.1016/j.bja.2018.02.064) Copyright © 2018 British Journal of Anaesthesia Terms and Conditions

Fig. 4 Homogeneity of lung aeration, as determined by global inhomogeneity index before induction of anaesthesia, during initial propofol, and subsequent xenon-based anaesthesia. BMI (kg m−2). *P<0.05; n.s.: not significant. British Journal of Anaesthesia 2018 120, 1394-1400DOI: (10.1016/j.bja.2018.02.064) Copyright © 2018 British Journal of Anaesthesia Terms and Conditions