Prolyl Isomerases and Nuclear Function

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Prolyl Isomerases and Nuclear Function Tony Hunter  Cell  Volume 92, Issue 2, Pages 141-143 (January 1998) DOI: 10.1016/S0092-8674(00)80906-X

Figure 1 Regulation of c-Myb DNA-Binding Activity by Cyp40 The three repeats of the N-terminal c-Myb DNA-binding domain are linked to the transactivation domain (AD) and the C-terminal negative regulatory domain (NRD), which interacts with the DBD via the EVES motif. The four mutations in the v-Myb DBD are indicated by short black bars. The N-terminal peptidyl-prolyl isomerase (PPIase) domain is shown as a Pacman linked to the C-terminal domain containing three tetratricopeptide (TPR) repeats (crosshatched boxes). DNA is shown as a horizontal bar. Cell 1998 92, 141-143DOI: (10.1016/S0092-8674(00)80906-X)