Fig. 1 Epigenomic and genomic variations between dwarf and normal whitefish species and their reciprocal hybrids. Epigenomic and genomic variations between.

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Fig. 1 Epigenomic and genomic variations between dwarf and normal whitefish species and their reciprocal hybrids. Epigenomic and genomic variations between dwarf and normal whitefish species and their reciprocal hybrids. (A) Principal components analysis (PCA) on 10,374 SNPs. (B) PCA on 423,652 CpGs. (C) Redundancy analysis (RDA) on 10,374 SNPs where genetic variance is explained by the variable lineage. (D) RDA on 423,652 CpGs where epigenetic variance is explained by the variable lineage. Blue circles represent dwarf individuals (DD), red squares represent normal individuals (NN), dark purple down-triangles represent normal ♀-dwarf hybrids (ND), and pale purple up-triangles represent dwarf ♀-normal hybrids (DN). (E) Distribution of CpG according to their methylation level for pure and hybrid whitefish groups represented by the same color used above. (F) Pairwise individual correlation between CpG methylation levels. The tree was constructed using UPGMA methods, and the correlation matrix of level of methylation was observed among individuals. M. Laporte et al. Sci Adv 2019;5:eaaw1644 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).