A, Number of published pediatric complementary medicine (CM) systematic reviews (SRs) from 1966 to 2015. 1966–2001 SR data are from Moher D, Soeken K, Sampson M, Ben-Porat L, Berman B. Assessing the quality of reports of systematic reviews in pediatric comp... A, Number of published pediatric complementary medicine (CM) systematic reviews (SRs) from 1966 to 2015. 1966–2001 SR data are from Moher D, Soeken K, Sampson M, Ben-Porat L, Berman B. Assessing the quality of reports of systematic reviews in pediatric complementary and alternative medicine. BMC Pediatr. 2002;2:3. 2001–2015 data were collected by the Complementary and Alternative Research and Education (CARE) Program for Integrative Health & Healing. B, Number of published pediatric CM RCTs from 1966 to 2015. 1966–2001 RCT data are from Sampson M, Campbell K, Ajiferuke I, Moher D. Randomized controlled trials in pediatric complementary and alternative medicine: Where can they be found? BMC Pediatr. 2003;3(1):10. 2001–2015 data were collected by the CARE Program for Integrative Health & Healing. Methods: Pediatric CM RCTs have been retrieved from (A) the Cochrane Central Register of Controlled Trials database using the tag “SR-COMPMED” and (B) through searches in Medline, Embase, and Cumulative Index to Nursing and Allied Health Literature. Pediatric CM SRs were retrieved from the Cochrane Database of Systematic Reviews, Medline, Embase, and Cumulative Index to Nursing and Allied Health Literature. All searches were limited to publications between April 2001 and December 2015. Search results were screened, and studies not matching the NCCIH1 definition were excluded. Agency for Healthcare Research and Quality monograph.55 Hilary McClafferty et al. Pediatrics doi:10.1542/peds.2017-1961 ©2017 by American Academy of Pediatrics