A 55-year-old man with a history of impotence, urinary bladder dysfunction, and obstipation for the past 6 years. A 55-year-old man with a history of impotence, urinary bladder dysfunction, and obstipation for the past 6 years. Most of the frontoparietal and occipital white matter is affected (A–D and G). The periventricular white matter looks less pathologic (B, C, G). The circular periventricular layers are best seen in a coronal plane (G). The leukodystrophic area continues in the temporal lobes (D, arrow). The corticospinal tracts show a high signal intensity in the internal capsules (C), mesencephalon (D), pons (E), and medulla oblongata (F). The upper (arrowhead) and middle cerebellar peduncles are affected (D and E). High signal intensities are seen in the corpus callosum (B). Its posterior part (B) is very thin.A–F, Fluid-attenuated inversion recovery (FLAIR), 10,000/140/2500.G, Turbo spin-echo (TSE), 8116/100. A. Melberg et al. AJNR Am J Neuroradiol 2006;27:904-911 ©2006 by American Society of Neuroradiology