Surface expression of chemokine receptors on M

Slides:

Advertisements

Similar presentations

High-dimensional analysis of lymphoid CD4+ T cells identified distinct TFH cell subsets in HIV+ patients and HCs. High-dimensional analysis of lymphoid.

Advertisements

Anti-CD40 and CpG induce activation of T cells in draining lymph nodes

IFN-γ and STAT1 are required for efficient induction of CXC chemokine receptor 3 (CXCR3) on CD4+ but not CD8+ T cells by Joseph Barbi, Steve Oghumu, Claudio.

Monocyte chemoattractant chemokines in cystic fibrosis

Blood-borne human plasma cells in steady state are derived from mucosal immune responses by Henrik E. Mei, Taketoshi Yoshida, Wondossen Sime, Falk Hiepe,

Lineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti–factor VIII immune responses by Ruth A. Ettinger,

Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells by Elke Scandella, Ying Men, Silke Gillessen,

IL-21 induces the expression of CX3CL1 in the muscle in EAM

IRF4 is required for anabolic induction of CD4+ T cells.

Use of EAS to define TCR-Vb3- and TCR-Cb1-expressing T cells

Figure 3 Decreased AHI1 in human CD4+ T cells is associated with decreased proliferation and increased IFNγ production Decreased AHI1 in human CD4+ T cells.

Soluble PD-1 ligands regulate T-cell function in Waldenstrom macroglobulinemia by Shahrzad Jalali, Tammy Price-Troska, Jonas Paludo, Jose Villasboas, Hyo-Jin.

Human dendritic cell subset 4 (DC4) correlates to a subset of CD14dim/−CD16++ monocytes Federica Calzetti, BS, Nicola Tamassia, PhD, Alessandra Micheletti,

Depo-Provera altered the expression of cell surface markers associated with HIV susceptibility. Depo-Provera altered the expression of cell surface markers.

Cetuximab treatment increases IFNγ receptor 1 expression.

Variable levels of cell surface and intracellular marker expression by HuT78 and HuT102 cells. Variable levels of cell surface and intracellular marker.

TIGIT expression in naive T cells is accelerated by coculture with si-tolerant T cells at an early-stimulation stage. TIGIT expression in naive T cells.

Human Treg cells express PlexinB1.

rSema4A increases the relative number of CD4+CD25+ HuT cells.

Figure 2 The frequency of helper T cells (Th) within CD4+ population and TCRγδ within CD3+ cells is affected by FTY and DMF treatment The frequency of.

Increased chemokine content and leukocyte infiltrate in D6-negative tumors. Increased chemokine content and leukocyte infiltrate in D6-negative tumors.

Volume 140, Issue 5, Pages e3 (May 2011)

Differential expression of functional chemokine receptors on human blood and lung group 2 innate lymphoid cells Cathryn A. Weston, PhD, Batika M.J. Rana,

Katherine G. MacDonald, BSc, Nicholas A. J

CD160−/− IELs have a defect in granzyme B production during L

Human mast cells drive memory CD4+ T cells toward an inflammatory IL-22+ phenotype Nicolas Gaudenzio, PhD, Camille Laurent, MD, Salvatore Valitutti,

Flow cytometric characterization of γδ T cells in our patient demonstrates specific expansion of a homogeneous Vδ2+ T cell population. Flow cytometric.

Flow cytometry analysis of TNF-β- and IL-10-producing CD33+ cells.

Elicited and steady-state transport of skin self-antigens in PYNOD-KO mice. Elicited and steady-state transport of skin self-antigens in PYNOD-KO mice.

T exosomes bind MAdCAM-1 via RA-increased integrin α4β7.

Inflammatory APC show highest expression of TNF superfamily ligands in the lung after LCMV infection. Inflammatory APC show highest expression of TNF superfamily.

Oral Tolerance Can Be Established via Gap Junction Transfer of Fed Antigens from CX3CR1+ Macrophages to CD103+ Dendritic Cells Elisa Mazzini, Lucia Massimiliano,

Fig. 2. IL-2/rapamycin–expanded T cells express homing receptors to traffic to lymphoma sites and are resistant to SN-38 toxicity. IL-2/rapamycin–expanded.

Peptide concentration controls digital NFAT1 nuclear translocation kinetics in a responder fraction of stimulated naive OT-I cells. Peptide concentration.

CXCR5 expression accelerates Eμ-Tcl1 leukemogenesis and is indispensable for tumor cell recruitment to lymphoid B-cell follicles. CXCR5 expression accelerates.

Figure 2 P2Y12 expression is upregulated in M2-polarized human microglia(A, B) Using TaqMan quantitative real-time PCR, P2Y12 expression was measured in.

Differential expression of TRM markers by donor- and recipient-derived T cells with time. Differential expression of TRM markers by donor- and recipient-derived.

The mucosal environment regulates CD160 expression on IELs

The microbiota downregulate CD160 expression on IELs

CD27 expression on bovine γδ and CD4 T cells ex vivo and in response to mitogen. CD27 expression on bovine γδ and CD4 T cells ex vivo and in response to.

AhR activation reduces lung DC gene and surface expression of DC-SIGN.

Fig. 4 Labeling of Msmeg with DMN-Tre is fast and specific and depends on Ag85A function. Labeling of Msmeg with DMN-Tre is fast and specific and depends.

PD-1 blockade results in increased expression of the chemokine receptor CXCR3. PD-1 blockade results in increased expression of the chemokine receptor.

IL-33, IL-25, and TSLP induce a distinct phenotypic and activation profile in human type 2 innate lymphoid cells by Ana Camelo, Guglielmo Rosignoli, Yoichiro.

CD8α+, CD8α−, and MoDCs from NOD.hCD205 mice express hCD205.

Senescence-associated defective HLA-DR upregulation does not modulate immunosuppressive properties of MSCs. (A) Fit and senescent MSCs were subjected to.

CD4+CLA+CD103+ T cells constitute a unique cell population in human blood. CD4+CLA+CD103+ T cells constitute a unique cell population in human blood. (A)

MK-8628 suppresses T lymphocyte proliferation.

CD27+ expression correlates with robust Ag-specific responses to M

Spontaneous and strong Tfh cell but not Tfr cell development in IL-2 KO mice. Spontaneous and strong Tfh cell but not Tfr cell development in IL-2 KO mice.

CD25 surface expression and TCR signal strength predict T helper differentiation and memory potential of early effector T cells in vivo. CD25 surface expression.

Overexpression of IL-27 upregulates expression of multiple IR by T cells in vivo. Overexpression of IL-27 upregulates expression of multiple IR by T cells.

BMS blocks functional responses in primary immune cells driven by IFNα

CD11b-mediated migratory property of peripheral blood B cells

Human Tfr cells do not express CD25.

Volume 25, Issue 6, Pages (June 2017)

Expression of XCR1 in normal ovarian surface epithelium and the IOSE and borderline EOC cell lines. Expression of XCR1 in normal ovarian surface epithelium.

Flow cytometry analysis of intracellular cytokine expression in control PBMC (left set of panels) and following either PMA-ionomycin activation (middle.

ALT-803 stimulates proliferation and activation of human NK cells and T cells in vitro. ALT-803 stimulates proliferation and activation of human NK cells.

Trametinib and combination promote moDC maturation and decrease moDC viability. Trametinib and combination promote moDC maturation and decrease moDC viability.

Mice with a B cell–specific loss of Ets1 have reduced marginal zone B cells and increased ASCs. (A) Flow cytometry analysis of CD21 versus CD23 in gated.

Expression of chemokine receptors in A-498 cell line.

Lin28b promotes the positive selection of CD5+ ImmB cells in neonatal mice. Lin28b promotes the positive selection of CD5+ ImmB cells in neonatal mice.

Mice with a B cell–specific deletion of Ets1 do not have increased CD4+ T cell activation. Mice with a B cell–specific deletion of Ets1 do not have increased.

IL-9–expressing TH cells are highly enriched in CCR4+/CCR8+ effector memory TH cells. IL-9–expressing THcells are highly enriched in CCR4+/CCR8+effector.

E2 induces IL-17–producing γδ+ T cells in the FGT

Meningeal γδ T cells are biased toward IL-17 production.

Fig. 3 Three small molecules inhibit the transport of CCR5 and do not affect transport of CCR1 or CXCR4. Three small molecules inhibit the transport of.

Lack of innate immune cell and receptor triggering by Adjuplex.

Bb monocolonization enhances Treg population in the cLP.

Presentation transcript:

Surface expression of chemokine receptors on M Surface expression of chemokine receptors on M. bovis–specific peripheral γδ and CD4 T cells. Surface expression of chemokine receptors on M. bovis–specific peripheral γδ and CD4 T cells. PBMCs were isolated from calves ∼8 wk after challenge with virulent M. bovis. Cells were stained with CellTrace dye and incubated with PPD-b for 6 d. Flow cytometry was used to study CXCR3 and CCR5 expression on M. bovis–specific CD4 and γδ T cells. Cells were surface stained and then analyzed by flow cytometry for CXCR3 and CCR5 expression. (A) Representative histograms of CXCR3 and CCR5 expression on Ag-responsive (blue solid line) and nonresponsive CD4 and γδ T cells (red solid line). Cumulative results from live γδ (B) and CD4 T cells (C), gated based on response to M. bovis (i.e., proliferating cells) and analyzed for CXCR3 or CRR5 expression. The fluorescence minus one (FMO) control is shown in gray shaded histograms. Data are presented as mean ± SEM mean fluorescence intensity (MFI) expression of cell surface markers. Results are representative of one independent experiment with n = 10. *p < 0.05, ***p < 0.001 indicate a significant difference (p < 0.05) from Ag-responsive cells compared with nonresponsive cells as determined by Student t test. Mariana Guerra-Maupome et al. ImmunoHorizons 2019;3:208-218 Copyright © 2019 The Authors