Hyperintensities in the deep WM involving the centrum semiovale in a 53-year-old man with DNS after CO poisoning. Hyperintensities in the deep WM involving the centrum semiovale in a 53-year-old man with DNS after CO poisoning. A, T2-weighted imaging within 24 hours after CO inhalation reveals slight hyperintensity in the bilateral deep WM and shows a necrotic focus in the left parietal lobe. B, At 2 days after the occurrence of DNS, hyperintense areas appear widespread in the bilateral deep WM. Brain atrophy is also apparent in the bilateral frontal lobes. T. Beppu AJNR Am J Neuroradiol 2014;35:625-631 ©2014 by American Society of Neuroradiology