Marijke Faas, Ph. D. , Annechien Bouman, M. D

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Presentation transcript:

The immune response during the luteal phase of the ovarian cycle: a Th2-type response?  Marijke Faas, Ph.D., Annechien Bouman, M.D., Henk Moesa, Maas Jan Heineman, Ph.D., Loe de Leij, Ph.D., Gerard Schuiling  Fertility and Sterility  Volume 74, Issue 5, Pages 1008-1013 (November 2000) DOI: 10.1016/S0015-0282(00)01553-3

Figure 1 Percentages of cytokine-producing cells (IFN-γ, IL-2, IL-4, and IL-10) of helper T-lymphocytes (top) and of cytotoxic T-lymphocytes (bottom) in the follicular phase and luteal phase of the normal ovarian cycle. □ = follicular phase; ■ = luteal phase. ∗Statistically significant difference compared with the follicular phase (Wilcoxon, P<.05). Faas. Ovarian cycle and the immune response. Fertil Steril 2000. Fertility and Sterility 2000 74, 1008-1013DOI: (10.1016/S0015-0282(00)01553-3)

Figure 2 Ratio of IFN-γ/IL-4–producing helper and cytotoxic T lymphocytes in the follicular phase and luteal phase of the normal ovarian cycle. □ = follicular phase; ■ = luteal phase. ∗Statistically significant difference compared with the luteal phase (Wilcoxon, P<.05). Faas. Ovarian cycle and the immune response. Fertil Steril 2000. Fertility and Sterility 2000 74, 1008-1013DOI: (10.1016/S0015-0282(00)01553-3)