CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX 1 ITMO Cancer.

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CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX 1 ITMO Cancer.

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CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX 1 ITMO Cancer Cancer organisation in France CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX AVIESAN: National Alliance for life and health sciences INCa: National Cancer Institute

CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX Overview of Cancer research in France 800 research teams researchers, MDs, Technicians and administrative staff 85 universities, 26 medical schools- 10 Institutions of which Inserm-CNRS … One single desk: AVIESAN Cancer National Cancer Institute – INCa: project funding A common strategy and a national cancer plan ( ), dedicated budget : 2,5 billion euros including 500 millions for research 2

CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX Accelerating translation of innovation to patients Research InfrastructuresTools to improve research Comprehensive Cancer research centres – 8 SIRIC Early phase clinical trial centres - 16 CLIP 2 Molecular Genetics Centres Clinical trial Registry Clinical research Cohorts Data processing centres Cooperative groups Clinical-biological Databases 3

CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX 833 Aviesan Cancer teams Teams teams teams 1-10 teams Paris area

CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX 10 actions for the next 5 years 5 Genomics and personalized medicine Medication, molecular pharmacology and biomarkers Metabolism, infection, inflammation, immunology and cancer Human and social sciences and epidemiology Epidemiology, epigenetics and environment

CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX 6 System Biology Physics/mathematics and cancer interfaces: Fundamental aspects and transfer toward clinical application Clinical research Training and technology transfer Society/patient information