Long term results with (pseudo) accommodative WIOL-CF Pasta, J., Hubackova, J., Stoy, V.A .*, Drunecky, T.* WIOL-CF seven years after implantation (Co-author‘s left eye in 2006) Department of Ophthalmology Charles University and Central Military Hospital, Prague, Czech Republic *Biovision s.r.o., Prague, Czech Republic ESCRS 2008 Berlin

WIOL-C/CF “Full Optics” hydrogel IOL (1992 – 2008) WIOL MAIN FEATURES: Large optical zone > 8.6 mm A constant = 120 High water content > 41 % Excellent biocompatibility Negatively charged surface Implantable through 2.6 mm incision Plasticized for implantation (CF model) Elastic properties with delayed recovery (“lazy rubber”) Grows and softens in the implanted state SHARP EDGE MENISCOID ANTERIOR SURFACE CONICAL FASETTE HYPERBOLOID SURFACE CONTACTING POSTERIOR CAPSULE OPTICAL TRANSITION ZONE METHODS Surgery from IX/2005 to VI/2007 51 eyes (30 patients) Age ranging from 50 to 71 years No macular pathology Surgery performed through 2,65 mm corneal tunnel Folded WIOL-CF implanted in plasticized state by Medicel injector (cartridge 2,2mm) AC constant 120

UCVA Far Vision Near Vision [%] 3

Comparison of monocular vs. binocular UCVA [%] Far Vision Near Vision J No. 4

Average contrast sensitivity levels of WIOL-CF patients Worse than monofocal artefakia On upper level of average population limit Better than cataractous eye Typical for aspherical lenses 5

SCHEIMPFLUG’S IMAGE OF WIOL-CF SPECTACLES FOR READING SPECTACLES FOR COMPUTER OVERALL PATIENT SATISFACTION RATE SCHEIMPFLUG’S IMAGE OF WIOL-CF 6

CONCLUSIONS THANK YOU FOR YOUR ATTENTION Pseudo-accommodation of WIOL-CF appears to be caused by a combination of multiple factors, i.e. A-P movement, polyfocal optics, pupil size changes and optics deformation by the action of the ciliary muscle The best results we found in the group of young and actively living patients Patients complain sometimes for optical disturbances with little influence on overall satisfaction at all WIOL-CF is potential IOL mainly for middle-age patient cataract surgery, actively living people cataract surgery, and for cataract patients with the risk of future vitreo-retinal surgery THANK YOU FOR YOUR ATTENTION 7