Tissues Tissue = A collection of cells that perform related functions, and are similar in structure Histology = The study of tissues The Four Primary Tissue Types Epithelial Connective Muscular Nervous
Epithelial Tissue Epithelium / -a = cell layer (barrier) Protection: covering or lining—inside and out Permeability control: selective secretion and absorption Sensation: touch receptors etc. and neuroepithelium of special senses Glands = secretory structure Specialized secretions
Structural Characteristics of Epithelia apical Cellularity Cell to cell contacts Polarity Support by connective tissue Avascular (esp. skin) Regeneration/repair basal BM
Polarity of Epithelial Cells
Classification of Epithelia The function of the epithelium determines which type. Typically classified according to 1. Number of cell layers Simple vs. Stratified 2. Shape of cell Squamous, cuboidal, columnar
Simple Squamous Epithelium Location: Lining of ventral body cavities, e.g. peritoneum Lining of blood vessels (endothelium) Alveoli
Lung
Function of Simple Squamous E. Friction reduction (cavity lining) Blood vessel permeability control (capillaries) Gas absorption and secretion (lung) Not very protective—only one cell thick
Simple Cuboidal Epithelium Function: Secretion Absorption Location: Lining of ducts Glands (salivary, pancreas, thyroid) Kidney tubules
Thyroid Follicle
Simple Columnar Epithelium Function: Secretion Absorption Location: GI tract Many excretory ducts
Pseudostratified Ciliated Columnar Epithelium Function: Mucociliary Blanket Mixture of cell types nuclei located at various distances from surface. Yet: all cells contact BM Location: Respiratory tract except for lungs
Stratified Squamous Epithelium Function Protection against abrasion, pathogens, chemicals, heat/cold… Keratinized vs. non-keratinized Location ? Where we need protection! Skin surface Entrances/exits of body, e.g. mouth, vagina
Stratified cuboidal and columnar: quite rare, found in glands and ducts Sweat gland
Transitional Epithelium Function ? Extreme expansion & recoil Layered appearance due to overcrowding. All cells contact BM. Location ? Bladder, ureters, renal pelvis
stretched
Glandular Epithelia Types of Glandular Secretions: Exocrine Endocrine Glands have ducts Secretion to the “outside” of the body Simple or compound Endocrine Glands have no ducts Hormones (into the bloodstream)
Location in the Body
Connective Tissue: Supports, protects, binds tissues Structural characteristics: Specialized cells Extracellular protein fibers (collagen) Ground substance (fluid-like) extracellular matrix
Functions of C.T. Structural framework for body (p77) Transport of fluids and dissolved materials Support and protection for organs Energy storage (fat) Defense
Classification of C.T. C.T. proper (viscous matrix with fibrous, insoluble proteins) Areolar (loose), reticular, dense, adipose Supporting C.T. (gelatinous or solid matrix) Cartilage, bone Fluid C.T. (watery matrix with dissolved proteins) Blood, lymph
Classification of Connective Tissue
Connective Tissue Proper. - viscous matrix Connective Tissue Proper - viscous matrix -Includes loose, reticular, dense C.T. Types of Fibers: Collagen Elastic Reticular Defense: Macrophages Plasma Cells Mast Cells Other WBC Think about dermis
Fluid C. T. Blood (Ch 17) Lymph (Ch 20)
Supporting C.T. Cartilage Bone (Chapter 5) Hyaline, cells in lacunae Articular cartilage, symphysis pubis Elastic Ear, larynx Fibrocartilage Intervertebral discs Bone (Chapter 5) Mineral matrix
Study individual types of c.t. in lab
Membranes = Combination of Epithelia & C.T. Mucous membranes, Lining of cavities that communicate with exterior Serous membranes, Lining of sealed, internal cavities Cutaneous membranes, Skin
Membranes, cont’d Know special names of serous membranes depending on location Also know difference between “parietal” and “visceral”
Mucous vs. Serous Membrane
Cutaneous & Synovial Membranes
C.T. Framework of Body Also: Hypodermis or subcutaneous layer
Muscle Tissue Three types: Skeletal Cardiac Smooth (not striated)
Skeletal Muscle Voluntary Heavily striated Multinucleate periphery of the cell
Cardiac Muscle Heart (Only) Involuntary Striated Intercalated disks Heavily branched Single central nucleus
Smooth Muscle Involuntary Esp. digestive system No striations Very slow Single central nucleus
Nervous Tissue (ch 12) Neurons Neuroglia Transmit electrical impulses Supportive cells of the nervous system
Neural Tissue