Anatomy and Physiology for Emergency Care

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Presentation transcript:

Anatomy and Physiology for Emergency Care Chapter 11 The Endocrine System

Objectives Compare the similarities between the endocrine and nervous systems Compare the major chemical classes of hormones Explain the general mechanisms of hormonal action Describe how endocrine organs are controlled

Objectives Discuss the location, hormones, and functions of the following glands and tissues: pituitary, thyroid, parathyroids, thymus, adrenals, kidneys, heart, pancreas, testes, ovaries, and pineal gland Explain how hormones interact to produce coordinated physiological responses

Objectives Identify the hormones that are especially important to normal growth, and discuss their roles Explain how the endocrine system responds to stress Discuss the results of abnormal hormone production Discuss the functional relationships between the endocrine system and other body systems

An Overview of the Endocrine System

An Overview of the Endocrine System Structure of Hormones Hormones and the Cell Membrane Hormones and Intracellular Receptors

An Overview of the Endocrine System Control of Endocrine Activity Direct Negative Feedback Control Hypothalamus and Endocrine Regulation

The Pituitary Gland Anterior Pituitary Gland Hypophyseal Portal System Hypothalamic Control of the Anterior Pituitary Hormones of the Anterior Pituitary TSH ACTH FSH LH PRL GH MSH

Anatomy and Orientation of the Pituitary Gland

Hypophyseal Portal System

Feedback and Control of Endocrine Secretions

The Pituitary Gland The Posterior Pituitary Gland ADH Oxytocin

Pituitary Hormones and their Targets

The Thyroid Gland Thyroid Follicles and Thyroid Hormones The C Cells of the Thyroid Gland: Calcitonin

Homeostatic Regulation of Calcium Ion Concentrations

The Parathyroid Glands PTH

The Thymus Relatively enormous in newborns Reaches maximum size just before puberty Thymosins Key role in development and maintenance of normal immunological defenses

The Adrenal Glands The Adrenal Cortex The Adrenal Medulla Corticosteroids Mineralcorticoids Androgens The Adrenal Medulla

The Kidneys Calcitriol Erythropoietin Renin

The Heart Cardiac muscle cells in right atrium Atrial natriuetic peptide (ANP)

Endocrine Tissues of the Digestive System The Pancreas Regulation of Blood Glucose Concentrations

Regulation of Blood Glucose Concentrations

Endocrine Tissues of the Reproductive System The Testes Interstitial cells Androgens Testosterone Sustentacular cells The Ovaries Follicles Estrogens Corpus luteum Progesterone

The Pineal Gland Melatonin Slows the timing of sexual maturity Acts as an antioxidant Establishes day-night cycles of activity

Patterns of Hormonal Interaction Hormones and Growth Growth hormones Thyroid hormones Insulin Parathyroid hormone Gonadal hormones Hormones and Behavior Hormones and Aging

General Adaptation Syndrome

Integration with other Systems

Summary

Emergency Care Applications Chapter 11

Overview of the Many Facets of Endocrine Systems Disorders

Diabetes Mellitus Type I Diabetes Mellitus Type II Diabetes Mellitus Emergency Complications of Diabetes Hypoglycemia (Insulin Shock) Diabetic Ketoacidosis (Diabetic Coma) Nonketotic Hyperosmolar Coma

Intravenous Glucose Administration

Disorders of the Thyroid Gland Grave’s Disease Thyrotoxic Crisis (Thyroid Storm) Hypothyroidism and Myxedema

Disorders of the Thyroid Gland

Disorders of the Adrenal Glands Hyperadrenalism (Cushing’s Syndrome) Adrenal Insufficiency (Addison’s Disease)

Summary