Kendler et al (1985) Genetic explanation of schizophrenia

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Presentation transcript:

Kendler et al (1985) Genetic explanation of schizophrenia

Evidence from family studies There is now evidence that there is a relationship between the biological relationship and the risk of developing schizophrenia. First-degree relatives (parents, siblings and offspring) share a average 50% of their genes and second- degree relatives share approximately 25% of genes. The rate of schizophrenia in the general population is about 1%.

Kendler et al (1985) Family studies report that first degree relatives of schizophrenia patients have a higher prevalence (amount) of personality disorders, e.g. schizophrenia/ paranoia. Shown that first- degree relatives of those who have schizophrenia are 18 times more at risk than distant relatives. Therefore suggesting that there may be a spectrum of disorders genetically related to schizophrenia.

Evaluation x Family studies are often inconclusive. x There may be other factors/ approaches that can cause individual's behaviour, such as poor socialisation/ family problems. For cognitive approach, individual’s thought processes may not be rational. It is a longitudinal study- so it can provide more reliable data, however because the study has collected data over many years the data can be out- dated.