Phytochemical investigations on six medicinal plants Mohammad Nur-e-Alam School of Chemistry Bangor University.

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Presentation transcript:

Phytochemical investigations on six medicinal plants Mohammad Nur-e-Alam School of Chemistry Bangor University

Extraction and Isolation in Carduus crispus

Carduuside A

EI MS Fragmentations

Important HOHAHA and HMBC Correlations

Carduuside B

Extraction and Isolation Scheme of Iris bungei

Iris bungei, Mongolian medicinal Plant Quinones Nur-e-Alam M, et. al. Chem. Pharm. Bull. 48, 2000;

Iris bungei, Mongolian Medicinal Plant Flavones Nur-e-Alam M, et. al. J. Nat. Prod. 64, 2001;

X-ray Crystal Structure of 5, 7 & 8 A molecule of DMSO is visible as solvent of crystallization

Iris bungei, Mongolian Medicinal Plant Peltogynoids Nur-e-Alam M, et. al. Chem. Pharm. Bull., 49, 2001;

X-ray Crystal Structure of 10 Crystal System: Monoclinic. Space group:P2 1/n, Final R factor:

Iris bungei, Mongolian Medicinal Plant Isoflavones Nur-e-Alam M, et. al. J. Nat. Prod. 64, 2001;

Withania coagulans, Pakistani medicinal plant UV, MeOH (log e):325 nm (3.84) and 276 (3.91) IR: (OH),2839 (CH), 1772 (C=O) and 1517 (C=C) FAB-ve MS: 1151, Base Peak m/z 414 HR-MS m/z , MF C 56 H 64 O 26, (Calcd )

1 H-NMR and 13 C-NMR

Important HMBC Corelation Nur-e-Alam M, et. al. Helv. Chim,. Acta, 86, 2003;

Compounds from Sophora alopecuroides Nur-e-Alam M, et. al. J. Nat. Prod. 63, 2000;

HMBC and X-ray Stracture of Novel compounds

Novel compounds from Ferula mongolica

Ferula mongolica Nur-e-Alam M, et. al. Helv. Chim,. Acta, 84, 2001;

Thank You Acknowledgements: Professor M Iqbal Chaudhary Professor Att-ur-Rahman and others lebfellows