ANTIGEN-ANTIBODY INTERACTION LECTURER: DAVID. OBJECTIVES.

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Presentation transcript:

ANTIGEN-ANTIBODY INTERACTION LECTURER: DAVID

OBJECTIVES

INNATE VERSUS ADAPTIVE RESPONSE INNATEADAPTIVE

ANTIBODY!

ANTIBODY STRUCTURE

WHAT IS AN ANTIBODY??

BUT WHAT IS AN ANTIGEN???

SUMMARY

ANTIBODY FUNCTIONS

NEUTRALIZATION

OPSONIZATION

COMPLEMENT

AGGLUTINATION

ABO BLOOD GROUPS

THERE ARE LOTS OF TYPES OF ANTIBODIES

IgG

IgA

IgM

IgE

IgD

OBJECTIVES

QUESTION Which immunoglobulin can cross the placenta?

ANSWER IgG

QUESTION If you mix a person with type A blood and anti-A antibodies, will agglutination occur?

ANSWER Yes

QUESTION What is the difference between neutralization and opsonization?

ANSWER Neutralization – antibody binds a toxin and makes it harmless Opsonization – antibody binds an antigen and targets it for phagocytosis

LAB TODAY Today you will be simulating the Ouchterlony test. This test is performed on an agar plate Antigen and antibodies are placed in well and allowed to diffuse. If an interaction occurs between an antibody/antigen, then a white line appears.