Pfizer’s Response to Emerging Infectious Diseases/Food Safety Shucheng Zhang, DVM, PhD VMRD, Pfizer Animal Health 10/10/2014

Rapidly Expanding Population Challenging Global Resources Population dynamics Source: UNEP/GRID 2

Migration into Urban Areas Taxes Social Infrastructure By 2050, the UN says, there may be 3.5 billion slumdwellers, out of a total urban population of about six billion. Land encroachments increase wildlife interactions

Demand for Protein Source: A dynamic meat market towards 2020, Kennes, Rapidly expanding middle class driving The need for Protein Emerging market economies - inrease % of the global middle class: 2000: 56% 2030: 93% China and India alone will account for 2/3 of this expansion

Global Food Supply In 2008, 21 Billion Production Animals, a global population of 6.5 billion people 50% Increase in Animal Protein by 2020

A rapidly expanding middle class will lead to an increase in trade Major global trade flows of dairy products, 2003 Global Meat Trade

At Least 60% Known Pathogens 75% of Emerging Pathogens Zoonotic Diseases Rabies, Tuberculosis, West Nile Virus, Influenza, SARS, Rift Valley Fever, Brucellosis, Anthrax

Thomas P. Monath, MD Emerging Infectious diseases

Recent Food Threat Examples Incidental – Beef – Chicken – Spinach – Nuts – Eggs Intentional – Salad Bar / Salmonella, Oregon – Melamine, Pet Food and Milk – Strychnine-laced Meatballs, Virginia Estimated 76 Million Cases of Food-borne Illness Annually

On newspaper Guangzhou Diary: Over 500 Million troubled eggs in the US On CCTV: Over 500 million eggs recalled Due to Salmonella problem…

Significance of EID to Global Health and Wellness Approximately 60% of all human infectious diseases and 75% of emerging infectious diseases are zoonoses. (SARS, Lyme) Significant disruptions to food security through: – Reduced productivity » Destroying a families livelihood E.g. PPR spreading across Africa » Negatively impacts sustainability e.g. BlueTongue – Disruption of food supply chains » E.g. FMD in South Africa, South Korea; hpAI – Foodborne illnesses » Real or perceived eg E.coli O157 and pH1N1 respectively 10/10/201411