© STMicroelectronics 2009 BRUNO MURARI 1 Game Controllers Mobile Phones/PMP Input Devices/ Remote Controllers ST sells to major OEMs in all these market segments Products Driving MEMS Adoption Notebook PCs Free fall detection

© STMicroelectronics 2009 BRUNO MURARI Easy navigation in mobile phones 2 Portrait / Landscape auto-detection On-screen map readjustment

© STMicroelectronics 2009 BRUNO MURARI 3 Take a better Picture Stabilized NOT Stabilized Piezoelectric Solution are power hungry and bulky

© STMicroelectronics 2009 BRUNO MURARI 4 ST MEMS History > 10x > 3x > 2x 31M$ 3M$ 102M$ 228M$

© STMicroelectronics 2009 BRUNO MURARI 5 ST: Top of the list

© STMicroelectronics 2009 BRUNO MURARI 6 Microelectronics and… Bio Systems One possible example

© STMicroelectronics 2009 BRUNO MURARI 7 Bio systems Heart Blood Insulin Certification Food contamination Control Process Monitor Seismology Landslides Avalanches Bio-defense Bio - WHITE Water Air Bio - RED People Bio - GREEN Animal Plants Some Common Technology Platforms

© STMicroelectronics 2009 BRUNO MURARI Healthcare: facts and figures The issues: –Aging population (worldwide) –Need to improve the quality of service –Need to provide additional services In 2007 $2 trillions spent in the USA on healthcare 25% of the national economy (USA) tied up in healthcare by 2025 Underdeveloped countries do not have enough healthcare professionals to serve the population in far-away regions 8

© STMicroelectronics 2009 BRUNO MURARI 9 Today… Physiological samples to Diagnostic Center DIAGNOSTIC CENTER SAMPLES EXTRACTION. IN SPECIALIZE D CENTERS.ASSISTED

© STMicroelectronics 2009 BRUNO MURARI 10 POINT OF CARE AT HOME … tomorrow.TOTALLY PORTABLE.EASY TO USE AUTO-MONITORING AUTOMATIC ANALYSIS. AT HOME-IN OFFICE. NOT ASSISTED MEDICAL CENTER Bio- Sensors “Bio-to-Bit”

© STMicroelectronics 2009 BRUNO MURARI 11 “Bio-to-Bit”: convergent technologies - Bio - Medicine - Pharma - Lab-On-Chip - Sensors - Actuators GPRS EDGE/3G network Internet Cellular RFID Ultra low power WPAN High bit rate (UWB) Bluetooth WPAN Low bit rate WLAN WLAN Bluetooth DVB-H GPS Connectivity

© STMicroelectronics 2009 BRUNO MURARI Bio-to-Bit Platforms 12 From specialized medical center to personal environment (body, home, office, car) Individual autonomy in the sample extraction (no needs of specialized assistance) ‘bit’ transmission instead of biological samples movement 1.Bio-sensors 2.Sensor networks (body gateway) 3.Connection through low power wireless

© STMicroelectronics 2009 BRUNO MURARI Bio-to-Bit: a few building blocks 13  Thermo-reactors (PCR for DNA - qPCR for DNA)  Electronic noses  Ethylometer  Pumps  Valves  Syringes  Wet-ability  Microfluidic (idrofilia, idrofobia)  Electro-Dielectrophoresys  Energy Scavenging (piezo, magnetic, electromagnetic, …)

© STMicroelectronics 2009 BRUNO MURARI 14 Bluetooth off-body sensing Glucose Weight Movements Temperature

© STMicroelectronics 2009 BRUNO MURARI And more… 15 Array of Smart Micro-Robotic Medical Instrumentation Main Vision System Assistive Platform Operative Platform Sealing Elements Multiple Wireless Modules

© STMicroelectronics 2009 BRUNO MURARI Conclusion Lateral thinking Radical innovation Cross-competences and multidisciplinarity Solid microelectronics technologies Answer to real needs of our society Improve the quality of our life 16

© STMicroelectronics 2009 BRUNO MURARI Conclusion 17