10.1 Behavior Cell-network Protein Gene G2G2 G3G3 G1G1 P1P1 Environment (stimuli, nutrients, temperature, etc.) G4G4 P2P2 P3P3 P4P4 C2C2 C3C3 C4C4 B2B2.

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Presentation transcript:

10.1 Behavior Cell-network Protein Gene G2G2 G3G3 G1G1 P1P1 Environment (stimuli, nutrients, temperature, etc.) G4G4 P2P2 P3P3 P4P4 C2C2 C3C3 C4C4 B2B2 B3B3 B4B4

10.2 Healthy queen (diploid) Nonhealthy drone (haploid) uurr X UR Unhealthy workers (diploid) uUrR BACKCROSS Healthy queen (diploid) uurr X ur uR Ur UR F1 drones from unfertilized eggs (haploid) EXPECTED: 25% 25% 25% 25% OBSERVED: 21% 31% 21% 27% r: removes dead larvae U: fails to uncapR: fails to removeu: uncaps cells

10.3 P (parental population) Character Frequency High Low F 1 (first filial generation) F 2 (second filial generation) Character Frequency Character Frequency Character Frequency Character Frequency

10.4

10.5 F1 cross

10.6

Selected linesAdh strainWild type 10.7

10.8 bmal1 clk CLOCK BMAL1 E-box per 1,2,3 cry 1,2 PER CRY (a) (b) Expression (% of maximum) Time (h) per PER BMAL1 bmal1

Acquisition training STMMTM LTM (spaced training) ARM (massed training) dunce rutabaga fasciclin II volado amnesiac radish CREB? 10.9

Training (Days) Recall (elevated CaMKII) Training (Days) Recall Training (Days) Recall Training (Days) Recall (a) (b) (c) (d) 10.10