Y. Duan et al. European Journal of Radiology (2011) Changes in cerebral hemodynamics after carotid stenting of symptomatic carotid artery.

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Y. Duan et al. European Journal of Radiology (2011) Changes in cerebral hemodynamics after carotid stenting of symptomatic carotid artery

words MTT Mean transit time CBF cerebral blood flow CBV cerebral blood volume ACA territory of anterior cerebral artery MCA territory of middle cerebral artery PCA territory of posterior cerebral artery frontal watershed posterior watershed

To evaluate changes in cerebral hemodynamics after carotid stenting of symptomatic carotid artery in the patients who underwent ischemic stroke caused by carotid artery stenosis purpuse

methods Twenty patients with unilateral symptomatic carotid artery stenosis received brain CT perfusion scan a week before and a week after carotid artery stenting.

Six vascular territories such as ACA territory,MCA erritory, PCA territory, basal ganglia, watershed between ACA and MCA territory(frontal watershed), watershed between MCA and PCA territory (posterior watershed) were chosen for comparison

methods Three absolute values including MTT, CBV and CBF were acquired and analyzed by use of the post-processing software.Relative parameter values were defined as rCBF, rCBV and rMTT through comparing absolute values in symptomatic hemispheres to which in asymptomatic hemispheres.Then the two sets of data before and after treatment with T test for analysist.

results The mean rMTT decreased significantly in ACA territory, MCA territory and two watershed after treatment, while the mean rCBF increased significantly in those areas. But the mean rCBV had no significant changes in all six vascular territories. In PCA territory, all the parameters had no significant changes.

conclusion Carotid artery stenting yields satisfactory cerebral perfusion in ACA territory, MCA territory,basal ganglia,frontal watershed and posterior watershed

Thanks