NORIP, Malmø 27/ NOBIDA Nordic Reference Interval Project Biobank and Database Common Nordic Reference Intervals NFKK meeting 27/ Pål Rustad Fürst Medical Laboratory, Oslo

NORIP, Malmø 27/ NOBIDA Nordic Reference Interval Project Bio- and Data Bank Established by NFKK Bio-bank location DEKS Danish Institute for External Quality Assurance for Laboratories in Health Care Herlev University hospital, Copenhagen Databank location Fürst Medical Laboratory, Oslo NOBIDA commitee Ulrik Gerdes (Denmark), Jón Jóhannes Jónsson (Iceland), Veli Kairisto (Finland), Arne Mårtensson (Sweden), Pål Rustad (Norway)

NORIP, Malmø 27/ Bio-bank Samples from each reference individual –7x1 mL serum –2x1 mL Li-heparin plasma –1 mL buffy coat Reference materials –NFKK Reference serum X: 3000x5 mL –HIGH, LOW, P: ~300x2,5 mL (~1500 mL in bulk)

NORIP, Malmø 27/ NOBIDA Nordic Reference Interval Project Bio- and Data Bank

NORIP, Malmø 27/ Data base Type of data Reference individuals –Data from questionnaire Measurement system –Instrument manufacturer and name –Method group and name Measurement values –Controls and reference samples

NORIP, Malmø 27/ Database Measurement values

NORIP, Malmø 27/ Application for sampels and data Application form: Applications at the moment 1. Comparisons with the experiences in the local Southern Osthrobothnia Project Requested: Data on all components 2. Establishment of reference intervals for CEA, CA125, MUC1, Thyroglobulin (and autobodies), NSE, PSA (total and free), SCCA, ProGRP, AFP, CA19.9, HCG. Requested: 250 samples for each gender. 3. Evaluation of formulas for calculation of creatinine clearance based on gender, age, weight and measured S-creatinine. Requested: All data on creatinine