Autologous adipose stem cells and polylactide discs in the replacement of the rabbit temporomandibular joint disc by Katja Ahtiainen, Jari Mauno, Ville.

Slides:



Advertisements
Similar presentations
Regeneration of Meniscal Cartilage with Use of a Collagen Scaffold. Analysis of Preliminary Data* by KEVIN R. STONE, J. RICHARD STEADMAN, WILLIAM G. RODKEY,
Advertisements

Using high-resolution displays for high-resolution cardiac data by Christopher Goodyer, John Hodrien, Jason Wood, Peter Kohl, and Ken Brodlie Philosophical.
Intimal hyperplasia following implantation of helical- centreline and straight-centreline stents in common carotid arteries in healthy pigs: influence.
Supermacroprous chitosan–agarose–gelatin cryogels: in vitro characterization and in vivo assessment for cartilage tissue engineering by Sumrita Bhat, Anuj.
Mathematical modelling of adult hippocampal neurogenesis: effects of altered stem cell dynamics on cell counts and bromodeoxyuridine-labelled cells by.
The Effect of Implants Loaded with Autologous Mesenchymal Stem Cells on the Healing of Canine Segmental Bone Defects* by SCOTT P. BRUDER, KARL H. KRAUS,
Taking a deep look: modern microscopy technologies to optimize the design and functionality of biocompatible scaffolds for tissue engineering in regenerative.
Osteoconductive phosphoserine-modified poly(ε-lysine) dendrons: synthesis, titanium oxide surface functionalization and response of osteoblast-like cell.
Extracellular Matrix Bioscaffolds for Orthopaedic Applications by Jolene E. Valentin, John S. Badylak, George P. McCabe, and Stephen F. Badylak J Bone.
The effects of vibration loading on adipose stem cell number, viability and differentiation towards bone-forming cells by Laura Tirkkonen, Heidi Halonen,
Allogeneic Mesenchymal Stem Cells Regenerate Bone in a Critical-Sized Canine Segmental Defect by Treena Livingston Arinzeh, Susan J. Peter, Michael P.
Simulation of lung alveolar epithelial wound healing in vitro by Sean H. J. Kim, Michael A. Matthay, Keith Mostov, and C. Anthony Hunt Interface Volume.
Use of kernel-based Bayesian models to predict late osteolysis after hip replacement by P. Aram, V. Kadirkamanathan, and J. M. Wilkinson Interface Volume.
Toxicity of used orthodontic archwires assessed by three- dimensional cell culture by Bart Vande Vannet, Nahid Mohebbian, and Heinrich Wehrbein Eur J Orthod.
Bone Marrow-Derived Mesenchymal Stem Cells Influence Early Tendon-Healing in a Rabbit Achilles Tendon Model by Alphonsus K.S. Chong, Abel D. Ang, James.
Recombinant Human Bone Morphogenetic Protein-2 Accelerates Healing in a Rabbit Ulnar Osteotomy Model by M. L. Bouxsein, T. J. Turek, C. A. Blake, D. D’Augusta,
A Granulomatous Mass Surrounding a Maverick Total Disc Replacement Causing Iliac Vein Occlusion and Spinal Stenosis by Michael R. Berry, Brian G. Peterson,
The Use of Bone Morphogenetic Protein in Lumbar Spine Surgery by Jeffrey A. Rihn, Charley Gates, Steven D. Glassman, Frank M. Phillips, James D. Schwender,
Transfer of LacZ Marker Gene to the Meniscus* by HIDEYUKI GOTO, FRANKLIN D. SHULER, CHANIN LAMSAM, HANS D. MOLLER, CHRISTOPHER NIYIBIZI, FREDDIE H. FU,
Paracrine Action Enhances the Effects of Autologous Mesenchymal Stem Cell Transplantation on Vascular Regeneration in Rat Model of Myocardial Infarction 
Illustration of a pure ground-glass nodule which developed a solid component. a) June 2004; b) October 2004; c) June 2005; d) July Illustration of.
From: Orbital Volume Augmentation After Injection of Human Orbital Adipose-Derived Stem Cells in Rabbits Invest. Ophthalmol. Vis. Sci ;54(4):
Objectives Methods Results Conclusion
CCN family 2/connective tissue growth factor (CCN2/CTGF) stimulates proliferation and differentiation of auricular chondrocytes  T. Fujisawa, Ph.D., D.D.S.,
Connexin43 hemichannels mediate small molecule exchange between chondrocytes and matrix in biomechanically-stimulated temporomandibular joint cartilage 
Single-stage cell-based cartilage repair in a rabbit model: cell tracking and in vivo chondrogenesis of human umbilical cord blood-derived mesenchymal.
Kenichi Fujii et al. JIMG 2015;8:
Paracrine Action Enhances the Effects of Autologous Mesenchymal Stem Cell Transplantation on Vascular Regeneration in Rat Model of Myocardial Infarction 
Céline Jumeau et al. BTS 2016;j.jacbts
Tumor risk by tissue engineering: cartilaginous differentiation of mesenchymal stem cells reduces tumor growth  I. Akay, D. Oxmann, A. Helfenstein, R.
Repair of full-thickness femoral condyle cartilage defects using allogeneic synovial cell- engineered tissue constructs  M. Pei, F. He, B.M. Boyce, V.L.
G.-I. Im, H.-J. Kim  Osteoarthritis and Cartilage 
Connexin43 hemichannels mediate small molecule exchange between chondrocytes and matrix in biomechanically-stimulated temporomandibular joint cartilage 
Toward scaffold-based meniscus repair: effect of human serum, hyaluronic acid and TGF-ß3 on cell recruitment and re-differentiation  U. Freymann, M. Endres,
Fig. 6. N95BA5 biocompatibility beyond intended use frame.
Isaac Perea-Gil et al. BTS 2016;1:
Volume 25, Issue 11, Pages (November 2017)
Histology samples stained with Masson trichrome.
Repair of full-thickness femoral condyle cartilage defects using allogeneic synovial cell- engineered tissue constructs  M. Pei, F. He, B.M. Boyce, V.L.
Z. Zhang, W. Liao, Z. Zhang, X. Duan, C. Hou 
Karl A. Nath, Anthony J. Croatt, Jill J. Haggard, Joseph P. Grande 
Lung-derived mesenchymal stem cells (MSC) display in vitro multilineage potential. Lung-derived mesenchymal stem cells (MSC) display in vitro multilineage.
Mesenchymal stem cells
Osteoarthritis and Cartilage
Changes of human menisci in osteoarthritic knee joints
Hyaline cartilage cells outperform mandibular condylar cartilage cells in a TMJ fibrocartilage tissue engineering application  L. Wang, M.S., M. Lazebnik,
Magnesium enhances adherence and cartilage formation of synovial mesenchymal stem cells through integrins  M. Shimaya, T. Muneta, S. Ichinose, K. Tsuji,
Increased Severity of Bleomycin-Induced Skin Fibrosis in Mice with Leukocyte-Specific Protein 1 Deficiency  JianFei Wang, Haiyan Jiao, Tara L. Stewart,
Steven S. Weber, MD, Alan J. Annenberg, MD, Creighton B
Control computed tomography of the nodular lesion in the right upper lobe after 3 months. a) Axial mediastinal window, b) axial lung window and c) coronal.
30-year-old man with 5-month history of pain in the lumbar area, buttock, and right leg. 30-year-old man with 5-month history of pain in the lumbar area,
Successful Mitral Valve Replacement in a Patient With Ehlers-Danlos Syndrome Type VI  Hiroshi Takano, MD, Yuji Miyamoto, MD, Yoshiki Sawa, MD, Norihide.
Smad3 Signal Transducer Regulates Skin Inflammation and Specific IgE Response in Murine Model of Atopic Dermatitis  Minna Anthoni, Guoying Wang, Chuxia.
The detached osteochondral fragment as a source of cells for autologous chondrocyte implantation (ACI) in the ankle joint  S. Giannini, M.D., R. Buda,
Collagen accumulation is reduced with UK
Fig. 6 Knockdown of nestin impaired tendon repair and regeneration in a rat model of patellar tendon defect. Knockdown of nestin impaired tendon repair.
Coronal (A, B) and sagittal (D) sections of MIP reformations of a MDCTA performed on a 4-row-detector system in a 54-year old woman (patient 10) with an.
Tomoregulin-1 improves cardiac pathological changes after pressure overload. Tomoregulin-1 improves cardiac pathological changes after pressure overload.
Characterization of zebrafish muscle wasting in krasG12V-induced HCC zebrafish. 4-month-old male adult krasG12V and WT zebrafish were treated with dox.
Radiographic and histologic appearance of remnant cartilage grafts at 8 weeks. Radiographic and histologic appearance of remnant cartilage grafts at 8.
Preoperative T2-weighted magnetic resonance imaging (MRI) (sagittal view) shows disc herniation at the L4-L5 disc level (A) and axial view of MRI shows.
Effect of berberine on white adipose tissue mass.
Fig. 1 Neu1−/− fibroblasts have characteristics of myofibroblasts.
Case 1. Case 1. Images of the brain of an 80-year-old man with a history of headache, seizure, and left hemiparesis for 2 years. A, Precontrast CT scan.
Céline Jumeau et al. BTS 2016;1:
A, Axial high-resolution MR imaging in a 5-month-old girl with clinically suspected right-sided brachial plexus palsy shows avulsion injury of the right.
Anti-aging effects of ingenol mebutate for patients with actinic keratosis  Miri Kim, MD, PhD, Yujin Jung, MD, Jongsic Kim, MD, Seo-won Jeong, BS, Yu Ri.
A–C, An example of MR images and histopathologic features of carotid plaque with mixed components. A–C, An example of MR images and histopathologic features.
BMX is a driver of castration resistance in vitro and in vivo.
A–D, An example of MR images and histopathologic features of plaque mainly consisting of myxomatous tissue. A–D, An example of MR images and histopathologic.
Presentation transcript:

Autologous adipose stem cells and polylactide discs in the replacement of the rabbit temporomandibular joint disc by Katja Ahtiainen, Jari Mauno, Ville Ellä, Jaana Hagström, Christian Lindqvist, Susanna Miettinen, Timo Ylikomi, Minna Kellomäki, and Riitta Seppänen Interface Volume 10(85): August 6, 2013 ©2013 by The Royal Society

(a) The excised TMJ disc next to the ASC disc implant. Ahtiainen K et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

The relative expression levels of (a) aggrecan, (b) type I and (c) II collagen of the ASC discs after one week pre-culture prior to implantation measured by qRT-PCR. Ahtiainen K et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

CBCT images of the operated TMJ joints in the six- and 12-month groups represented as (a,e) axial and (c,g) coronal views as well as sagittal views of the (b,f) right and (d,h) left TMJs treated with control and differentiated ASC discs, respectively. Ahtiainen K et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

The sagittal histological sections of the TMJ area stained with Masson's trichrome. Ahtiainen K et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society

(a,b) The remnants of the ASC discs stained with haematoxylin–eosin of the control and (c,d) differentiated ASCs discs after (a,c) six and (b,d) 12 months of implantation. Ahtiainen K et al. J. R. Soc. Interface 2013;10: ©2013 by The Royal Society