Thoracic Surgery Innovations
Innovations VATS LVRS Chemotherapy Radiotherapy PET Small Cell N2 Stents & Lasers Stapler In Oesophagogastrectomy Epidural SVC stents
VATS Sympathectomy Pleurectomy Lobectomy Biopsy mass lung
Pneumothorax
Pleurectomy VAT Muscle sparing Mini Full Thoracotomy
VAT Lobectomy
Biopsy Lung / Pleura
LVRS
LVRS
LVRS Criteria Dyspnoeic on daily activities Age < 75 No bullae > 5cm Generalised emphysema with regional heterogeneity TLC > 125% FEV1 < 30 % PaCO2 < 50 mmHg, PaO2 > 40 mmHg on air No CAD or Pulmonary hypertension Steroid < 15 mg/day
LVRS Unilateral / Bilateral Thoracotomy / Sternotomy / VAT Role of Physio
Chemotherapy and Radiotherapy Preoperative Neoadjuvant Operative Postoperative Adjuvant
Chemotherapy Numerous agents Adjuvant Neoadjuvant Stage IIIA (N2) Stage II (T2N0) ? Role in N2 disease All oat cell Neoadjuvant Stage IIIA (N2) If respond are resected No residual tumour at surgery means prolonged survival Experimental
Radiotherapy External beam external rays Single / multiple beam / Fraction No Brachy local ie intra bronchial Interstitial directly into tumour Intra cavity in bronchus Adjuvant Postoperative Neoadjuvant Preoperative
Radiotherapy Primary treatment Adjuvant for N1 / N2 Stage 1 and 2 Refuse or unfit for surgery Failure 30 % stage 1 (T1N0), 70% stage 2 (T2N0) 5 year survival 5 to 40% Adjuvant for N1 / N2 Reduces rate local recurrence Survival unchanged ? Role in +Ve resection margins
Radiotherapy Neoadjuvant Palliative Brachytherapy T3 Pancoast prior to surgery Palliative Symptomatic relief Pain, haemoptysis, bronchial, SVC obstruction Bone met pain Brachytherapy Local application high local dose
Chemotherapy and Radiotherapy Adjuvant Neoadjuvant Sequential / concurrent / alternating Good performance status Not standard practice May increase risk surgery
PET 2-(fluorine-18) fluo-2-deoxy-D-glucose (18-FDG) 18-FDG competes with glucose for facilitated transport into tumour cells and also competes with glucose for phosphorylation by hexokinase Positive and negative predictive power
Small Cell Lung Cancer
Small Cell All need : Mediasteinoscopy CT head Bone scan
Pre operative N2 Young patients Pre op chemo downstage No evidence
Stents & Lasers Malignant terminal conditions that are inoperable Benign inoperable conditions
Tracheal obstruction-malignant - Pre and post Nd:Yag laser
Left main bronchus extensive squamous cell carcinoma Metal stent in left main
Stapler In Oesophagogastrectomy
Epidural Pain Poor PFTs Cardiac history Contraindications Low risk On anticoagulants Consent Anatomical Infective
SVC Stents
Any Questions ?
Next Week 2nd March Inotropes ITU seminar room