Dyspepsia: an underestimated problem among end-stage renal disease patients Paulo Santos Federal University of Ceará, Brazil.

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Presentation transcript:

Dyspepsia: an underestimated problem among end-stage renal disease patients Paulo Santos Federal University of Ceará, Brazil

Highly prevalent Great impact on quality of life

Prevalence In the literature: between 50% and 70% VanVlem et al Am J Kidney Dis 2000; 36:962 Cano et al Am J Gastroenterol :1990

Impact on Quality of Life Santos et al. Brazilian Congress of Nephrology 2012

What is dyspepsia?

Constellation of symptoms – Upper abdominal pain; Nausea; Vomiting; Upper abdominal bloating; Early satiety Tack et al. Gastroenterology 2006; 130:1466

WHY? I.Gastric emptying delay II.Hypervolemia

WHY? I.Gastric emptying delay II.Hypervolemia

Clinical implications I.It is very easy to search for symptoms of dyspepsia, so it should be done often II.Our finding raises the question about the main role of prokinetics in dyspepsia cases

WHY? I.Gastric emptying delay II.Hypervolemia

WHY? I.Gastric emptying delay II.Hypervolemia

Volemic status

Clinical implications I.Functional dyspepsia could be an alert of the need to revise the prescribed dry-weight of patients on HD II.Dyspeptic symptoms could be another tool to help estimate the optimal dry weight of patients on HD

IMPACTS ON NUTRITIONAL STATUS?

Clinical implication I.Screening of dyspeptic symptoms can be used as a tool for identification of patients on HD who are at risk of malnutrition