EX. 20 Antibiotic Disk Sensitivity

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Presentation transcript:

EX. 20 Antibiotic Disk Sensitivity

Antibiotics Naturally occurring compounds produced by bacteria and or fungi, that kill or inhibit other microbes Many Antibiotics are produced by 2 Genera of Bacteria Streptomyces Bacillus 1 Fungal Genus Penicillium

Common Antibiotics Stretomycin – Streptomyces Bacitracin - Bacillus Penicillin - Penicillium Protein synthesis 70S Ribosme Cell Wall synthesis

Selective toxicity The antibiotic must harm the pathogen without harming the host cell Antibiotics do this by: 1. Attacking the 70S Ribosome (Protein synthesis) 2. Attacking the Cell Wall

Kirby-Bauer Antibiotic Disk Sensitivity Test

Kirby-Bauer Antibiotic Disk Sensitivity Test

MIC Minimum Inhibitory Concentration Least amount of an antibiotic that will inhibit the growth of a microbe

MRSA Vancomycin VRE Methicillin Resistant Staphylococcus aureus Last line of defense against MRSA – which has led to VRE Vancomycin Resistant Enterococci

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