Powerful Skin Cancer Protection by a CPD-Photolyase Transgene Judith Jans, Wouter Schul, Yurda-Gul Sert, Yvonne Rijksen, Heggert Rebel, Andre P.M. Eker,

Slides:

Advertisements

Similar presentations

The solution structure of serine protease PB92 from Bacillus alcalophilus presents a rigid fold with a flexible substrate-binding site John R Martin, Frans.

Advertisements

Rapid Decrease in Delivery of Chemotherapy to Tumors after Anti-VEGF Therapy: Implications for Scheduling of Anti-Angiogenic Drugs Astrid A.M. Van der.

ATP-Induced Conformational Dynamics in the AAA+ Motor Unit of Magnesium Chelatase Joakim Lundqvist, Hans Elmlund, Ragna Peterson Wulff, Lisa Berglund,

Comparison between Actin Filament Models: Coarse-Graining Reveals Essential Differences Marissa G. Saunders, Gregory A. Voth Structure Volume 20, Issue.

Genome-wide Prediction of Mammalian Enhancers Based on Analysis of Transcription- Factor Binding Affinity Outi Hallikas, Kimmo Palin, Natalia Sinjushina,

Vesicle-Mediated Export and Assembly of Pore-Forming Oligomers of the Enterobacterial ClyA Cytotoxin Sun Nyunt Wai, Barbro Lindmark, Tomas Söderblom, Akemi.

Spatial Separation of HLA-DM/HLA-DR Interactions within MIIC and Phagosome- Induced Immune Escape Wilbert Zwart, Alexander Griekspoor, Coenraad Kuijl,

Complex N-Glycan Number and Degree of Branching Cooperate to Regulate Cell Proliferation and Differentiation Ken S. Lau, Emily A. Partridge, Ani Grigorian,

A Microscale Human Liver Platform that Supports the Hepatic Stages of Plasmodium falciparum and vivax Sandra March, Shengyong Ng, Soundarapandian Velmurugan,

Absence of the Endothelial Oxidase AOC3 Leads to Abnormal Leukocyte Traffic In Vivo Craig M. Stolen, Fumiko Marttila-Ichihara, Kaisa Koskinen, Gennady.

Pharmacological strategies for targeting BAT thermogenesis Andrew Whittle, Joana Relat-Pardo, Antonio Vidal-Puig Trends in Pharmacological Sciences Volume.

LRP6 Enhances Glucose Metabolism by Promoting TCF7L2-Dependent Insulin Receptor Expression and IGF Receptor Stabilization in Humans Rajvir Singh, Renata.

A Tick Mannose-Binding Lectin Inhibitor Interferes with the Vertebrate Complement Cascade to Enhance Transmission of the Lyme Disease Agent Tim J. Schuijt,

Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes Jessica Quintin, Sadia Saeed, Joost H.A. Martens,

DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia Maria E. Figueroa, Sanne Lugthart, Yushan Li, Claudia Erpelinck-Verschueren,

Sequential Action of Two Flavoenzymes, PgaE and PgaM, in Angucycline Biosynthesis: Chemoenzymatic Synthesis of Gaudimycin C Pauli Kallio, Zhanliang Liu,

Characterization of the Alnumycin Gene Cluster Reveals Unusual Gene Products for Pyran Ring Formation and Dioxan Biosynthesis Terhi Oja, Kaisa Palmu, Hanna.

Endogenous WNT Signals Mediate BMP-Induced and Spontaneous Differentiation of Epiblast Stem Cells and Human Embryonic Stem Cells Dorota Kurek, Alex Neagu,

M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells Nicole van der Wel, David Hava, Diane Houben, Donna Fluitsma,

An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria Jaan-Olle Andressoo,

Unexpected Membrane Dynamics Unveiled by Membrane Nanotube Extrusion Clément Campillo, Pierre Sens, Darius Köster, Léa-Laetitia Pontani, Daniel Lévy, Patricia.

Volume 23, Issue 24, Pages (December 2013)

A Cortical Core for Dynamic Integration of Functional Networks in the Resting Human Brain Francesco de Pasquale, Stefania Della Penna, Abraham Z. Snyder,

Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence G. Weeda, I. Donker, J. de Wit,

Structure of an Anti-Lewis X Fab Fragment in Complex with Its Lewis X Antigen Anne-Marie M van Roon, Navraj S Pannu, Johannes P.M de Vrind, Gijs A van.

History-Dependent Catastrophes Regulate Axonal Microtubule Behavior Tatiana Stepanova, Ihor Smal, Jeffrey van Haren, Umut Akinci, Zhe Liu, Marja Miedema,

The Macrophage Mannose Receptor Induces IL-17 in Response to Candida albicans Frank L. van de Veerdonk, Renoud J. Marijnissen, Bart Jan Kullberg, Hans.

Lessons from Hereditary Colorectal Cancer

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Stem cell-based biological tooth repair and regeneration

Proteasome Inhibitors: An Expanding Army Attacking a Unique Target Alexei F. Kisselev, Wouter A. van der Linden, Herman S. Overkleeft Chemistry & Biology.

Healthy clocks, healthy body, healthy mind Akhilesh B. Reddy, John S. O’Neill Trends in Cell Biology Volume 20, Issue 1, Pages (January 2010) DOI:

Hoxb8 Is Required for Normal Grooming Behavior in Mice Joy M. Greer, Mario R. Capecchi Neuron Volume 33, Issue 1, Pages (January 2002) DOI: /S (01)

HERG Channel (Dys)function Revealed by Dynamic Action Potential Clamp Technique Géza Berecki, Jan G. Zegers, Arie O. Verkerk, Zahurul A. Bhuiyan, Berend.

Codon usage limitation in the expression of HIV-1 envelope glycoprotein Jürgen Haas, Eun-Chung Park, Brian Seed Current Biology Volume 6, Issue 3, Pages.

Genetic testing for high-risk colon cancer patients1 William M. Grady Gastroenterology Volume 124, Issue 6, Pages (May 2003) DOI: /S (03)

Chapter 1: Definition and classification of CKD Kidney International Supplements Volume 3, Issue 1, Pages (January 2013) DOI: /kisup

A Conditional Mouse Model for Malignant Mesothelioma Johan Jongsma, Erwin van Montfort, Marc Vooijs, John Zevenhoven, Paul Krimpenfort, Martin van der.

Patient request for pharmacist counseling and satisfaction: Automated prescription delivery system versus regular pick-up counter Jan D. Hirsch, PhD Journal.

Metastatic melanoma treatment: Combining old and new therapies Ryan J. Davey, Andre van der Westhuizen, Nikola A. Bowden Critical Reviews in Oncology /

The relationship between maintenance dosages of three vitamin K antagonists: Acenocoumarol, warfarin and phenprocoumon Yvonne van Leeuwen, Frits R. Rosendaal,

Hyperbaric Oxygenation in Cardiac and Pulmonary Disease

Volume 151, Issue 3, Pages (March 2017)

P. Sooriakumaran, R. Kaba International Journal of Surgery

A randomized multicenter study of the outcome of brachial-basilic arteriovenous fistula and prosthetic brachial-antecubital forearm loop as vascular access.

The eighth edition TNM stage classification for lung cancer: What does it mean on main street? Frank C. Detterbeck, MD The Journal of Thoracic and Cardiovascular.

A Reliability Look at Energy Development

Volume 74, Issue 6, Pages (June 1998)

Esther Leushuis, M. D. , Jan Willem van der Steeg, M. D

Physics and Imaging in Radiation Oncology

Decline in risk of recurrent cardiovascular events in the period 1996 to 2014 partly explained by better treatment of risk factors and less subclinical.

Frank Detterbeck, MD Journal of Thoracic Oncology

The influence of preoperative weight loss on the postoperative course after esophageal cancer resection Maartje K. van der Schaaf, MD, Hugo W. Tilanus,

Insight Into Advance Care Planning for Patients on Dialysis

Single UVB Overexposure Stimulates Melanocyte Proliferation in Murine Skin, in Contrast to Fractionated or UVA-1 Exposure Arne van Schanke, Marjan J.

A Markov Decision Model to Guide Treatment of Recurrent Colonic Diverticulitis Caroline S. Andeweg, Johannes Groenewoud, Gert Jan van der Wilt, Harry.

Volume 152, Issue 1, (January 2013)

Judith H. J. Roelofzen, Katja K. H. Aben, Ursula T. H

Azathioprine-Induced Microsatellite Instability Is Not Observed in Skin Carcinomas of Organ Transplant Recipients Hermina C. Wisgerhof, Liesbeth Hameetman,

Gastrointestinal Endoscopy

Enhanced Global Genome Nucleotide Excision Repair Reduces UV Carcinogenesis and Nullifies Strand Bias in p53 Mutations in Csb−/- Mice Alex Pines, Liesbeth.

A retrospective study on surgical outcomes and patient satisfaction of EGIS® ADM in one-stage implant-based breast reconstruction Vera L. Negenborn,

Neovaginal Sparing in a Transgender Woman With Ulcerative Colitis

Table of contents The Journal for Nurse Practitioners

Association of Transcription-Coupled Repair but Not Global Genome Repair with Ultraviolet-B-Induced Langerhans Cell Depletion and Local Immunosuppression

Baseline Characteristics and Mortality Outcomes of Control Group Participants and Eligible Non-Responders in the NELSON Lung Cancer Screening Study Uraujh.

Cancer therapy: Less blood means more sanguinity

Trichomegaly of the Eyelashes After Treatment with Erlotinib in Non-small Cell Lung Cancer Judith Elizabeth Carser, MB, BCh, MRCR, Yvonne Jane Summers,

Powerful Skin Cancer Protection by a CPD-Photolyase Transgene

Volume 148, Issue 1, (January 2012)

Presentation transcript:

Powerful Skin Cancer Protection by a CPD-Photolyase Transgene Judith Jans, Wouter Schul, Yurda-Gul Sert, Yvonne Rijksen, Heggert Rebel, Andre P.M. Eker, Satoshi Nakajima, Harry van Steeg, Frank R. de Gruijl, Akira Yasui, Jan H.J. Hoeijmakers, Gijsbertus T.J. van der Horst Current Biology Volume 15, Issue 2, Pages (January 2005) DOI: /j.cub

Figure 1 Current Biology , DOI: ( /j.cub )

Figure 2 Current Biology , DOI: ( /j.cub )

Figure 3 Current Biology , DOI: ( /j.cub )

Figure 4 Current Biology , DOI: ( /j.cub )

Figure 5 Current Biology , DOI: ( /j.cub )

Figure 6 Current Biology , DOI: ( /j.cub )