Genetic Linkage to Chromosome 22q12 for a Heavy-Smoking Quantitative Trait in Two Independent Samples Scott F. Saccone, Michele L. Pergadia, Anu Loukola,

Slides:



Advertisements
Similar presentations
Homozygous Mutations in Fibroblast Growth Factor 3 Are Associated with a New Form of Syndromic Deafness Characterized by Inner Ear Agenesis, Microtia,
Advertisements

Genomewide Linkage Analysis of Bipolar Disorder by Use of a High-Density Single- Nucleotide–Polymorphism (SNP) Genotyping Assay: A Comparison with Microsatellite.
Linkage Findings on Chromosome 2 Suggest a Gene Predisposing To Multiple Behavioral Undercontrol Phenotypes DM Dick 1, G Dunn 1, A Goate 1, T Foroud 2,
Novel PMS2 Pseudogenes Can Conceal Recessive Mutations Causing a Distinctive Childhood Cancer Syndrome Michel De Vos, Bruce E. Hayward, Susan Picton, Eamonn.
DSM-IV Nicotine Withdrawal and Alcohol Dependence: Association Findings with the Nicotinic Acetylcholine Alpha-3, Alpha-5, Beta-4 Receptor Gene Cluster.
Nuclear and Mitochondrial DNA Analysis of a 2,000-Year-Old Necropolis in the Egyin Gol Valley of Mongolia Christine Keyser-Tracqui, Eric Crubézy, Bertrand.
Length Distributions of Identity by Descent Reveal Fine-Scale Demographic History Pier Francesco Palamara, Todd Lencz, Ariel Darvasi, Itsik Pe’er The American.
Previous Estimates of Mitochondrial DNA Mutation Level Variance Did Not Account for Sampling Error: Comparing the mtDNA Genetic Bottleneck in Mice and.
Linkage Signals for Illicit Drug Phenotypes The Nicotine Addiction Genetics (NAG) Project Arpana Agrawal, Andrew C. Heath, Scott Saccone, Michele Pergadia,
The Novel Genetic Disorder Microhydranencephaly Maps to Chromosome 16p  
Connexin Mutations in Skin Disease and Hearing Loss David P. Kelsell, Wei-Li Di, Mark J. Houseman The American Journal of Human Genetics Volume 68, Issue.
Alcohol and Nicotine Use and Dependence: Shared Genetic and Other Risk Factors Pamela Madden, Ph.D. Washington University School of Medicine.
Functional Analysis of the Neurofibromatosis Type 2 Protein by Means of Disease- Causing Point Mutations Renee P. Stokowski, David R. Cox The American.
Gene Preference in Maple Syrup Urine Disease Mary M. Nellis, Dean J. Danner The American Journal of Human Genetics Volume 68, Issue 1, Pages (January.
Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part I: Methods and Power Analysis Douglas F. Levinson, Matthew D. Levinson, Ricardo Segurado,
Genomewide Comparison of DNA Sequences between Humans and Chimpanzees Ingo Ebersberger, Dirk Metzler, Carsten Schwarz, Svante Pääbo The American Journal.
Fragile X and X-Linked Intellectual Disability: Four Decades of Discovery Herbert A. Lubs, Roger E. Stevenson, Charles E. Schwartz The American Journal.
How surgeons can find information online? Martin Hewitt International Journal of Surgery Volume 5, Issue 6, Pages (December 2007) DOI: /j.ijsu
The Duty to Recontact: Attitudes of Genetics Service Providers Jennifer L. Fitzpatrick, Cecil Hahn, Teresa Costa, Marlene J. Huggins The American Journal.
Peopling of Sahul: mtDNA Variation in Aboriginal Australian and Papua New Guinean Populations Alan J. Redd, Mark Stoneking The American Journal of Human.
Quantitative-Trait-Locus Analysis of Body-Mass Index and of Stature, by Combined Analysis of Genome Scans of Five Finnish Study Groups  Markus Perola,
The Trimmed-Haplotype Test for Linkage Disequilibrium
Two Loci on Chromosomes 2 and X for Premature Coronary Heart Disease Identified in Early- and Late-Settlement Populations of Finland  Päivi Pajukanta,
Genetic Linkage to Chromosome 22q12 for a Heavy-Smoking Quantitative Trait in Two Independent Samples  Scott F. Saccone, Michele L. Pergadia, Anu Loukola,
Anna Middleton, J. Hewison, R.F. Mueller 
Quantitative-Trait Loci Influencing Body-Mass Index Reside on Chromosomes 7 and 13: The National Heart, Lung, and Blood Institute Family Heart Study 
Anna Middleton, J. Hewison, R.F. Mueller 
Daniel J. Schaid, Charles M. Rowland, David E. Tines, Robert M
Consistently Replicating Locus Linked to Migraine on 10q22-q23
Optimized Group Sequential Study Designs for Tests of Genetic Linkage and Association in Complex Diseases  Inke R. König, Helmut Schäfer, Hans-Helge Müller,
A Major Susceptibility Locus Influencing Plasma Triglyceride Concentrations Is Located on Chromosome 15q in Mexican Americans  Ravindranath Duggirala,
Common Genetic Variants Influence Whorls in Fingerprint Patterns
Genetic Linkage Analysis of a Dichotomous Trait Incorporating a Tightly Linked Quantitative Trait in Affected Sib Pairs  Jian Huang, Yanming Jiang  The.
2016 Curt Stern Award Address: From Rare to Common Diseases: Translating Genetic Discovery to Therapy1  Brendan Lee  The American Journal of Human Genetics 
Quantitative-Trait Loci Influencing Body-Mass Index Reside on Chromosomes 7 and 13: The National Heart, Lung, and Blood Institute Family Heart Study 
Meta-analysis of Genetic-Linkage Analysis of Quantitative-Trait Loci
Accounting for Linkage in Family-Based Tests of Association with Missing Parental Genotypes  Eden R. Martin, Meredyth P. Bass, Elizabeth R. Hauser, Norman.
Ren-Hua Chung, Richard W. Morris, Li Zhang, Yi-Ju Li, Eden R. Martin 
Linkage Thresholds for Two-stage Genome Scans
A Combined Linkage-Physical Map of the Human Genome
Genetics, Individuality, and Medicine in the 21st Century*
Dale R. Nyholt, Katherine I. Morley, Manuel A. R. Ferreira, Sarah E
The American Journal of Human Genetics 
A Quantitative-Trait Locus in the Human Factor XII Gene Influences Both Plasma Factor XII Levels and Susceptibility to Thrombotic Disease  José Manuel.
Danielle Posthuma, Michelle Luciano, Eco J. C. de Geus, Margie J
Consistently Replicating Locus Linked to Migraine on 10q22-q23
A Variant in LIN28B Is Associated with 2D:4D Finger-Length Ratio, a Putative Retrospective Biomarker of Prenatal Testosterone Exposure  Sarah E. Medland,
Dan-Yu Lin, Zheng-Zheng Tang  The American Journal of Human Genetics 
The SNP Endgame: A Multidisciplinary Approach*
Family-Based Tests of Association in the Presence of Linkage
Erratum The American Journal of Human Genetics
Michael P. Epstein, Xihong Lin, Michael Boehnke 
Two Loci on Chromosomes 2 and X for Premature Coronary Heart Disease Identified in Early- and Late-Settlement Populations of Finland  Päivi Pajukanta,
A Versatile Gene-Based Test for Genome-wide Association Studies
Volume 69, Issue 12, Pages (June 2006)
David B. Allison, Bonnie Thiel, Pamela St. Jean, Robert C
Greg L. Loeben, Theresa M. Marteau, Benjamin S. Wilfond 
Yujun Shao, Kimberly L. Raiford, Chantelle M. Wolpert, Heidi A
Passing the torch The Journal of Thoracic and Cardiovascular Surgery
Discussion The Journal of Thoracic and Cardiovascular Surgery
Genome-wide Linkage and Association Analyses Implicate FASN in Predisposition to Uterine Leiomyomata  Stacey L. Eggert, Karen L. Huyck, Priya Somasundaram,
Sarah E. Medland, Dale R. Nyholt, Jodie N. Painter, Brian P
Alice S. Whittemore, Jerry Halpern 
Genetic Linkage Analysis of a Dichotomous Trait Incorporating a Tightly Linked Quantitative Trait in Affected Sib Pairs  Jian Huang, Yanming Jiang  The.
Anna Middleton, J. Hewison, R.F. Mueller 
Sanjay Shete, Xiaojun Zhou, Christopher I. Amos 
Zuoheng Wang, Mary Sara McPeek  The American Journal of Human Genetics 
A Chromosomal Deletion Map of Human Malformations
On Genome-wide Association Studies for Family-Based Designs: An Integrative Analysis Approach Combining Ascertained Family Samples with Unselected Controls 
The Size Distribution of Homozygous Segments in the Human Genome
Presentation transcript:

Genetic Linkage to Chromosome 22q12 for a Heavy-Smoking Quantitative Trait in Two Independent Samples Scott F. Saccone, Michele L. Pergadia, Anu Loukola, Ulla Broms, Grant W. Montgomery, Jen C. Wang, Arpana Agrawal, Danielle M. Dick, Andrew C. Heath, Alexandre A. Todorov, Heidi Maunu, Kauko Heikkilä, Katherine I. Morley, John P. Rice, Richard D. Todd, Jaakko Kaprio, Leena Peltonen, Nicholas G. Martin, Alison M. Goate, Pamela A.F. Madden The American Journal of Human Genetics Volume 80, Issue 5, Pages (May 2007) DOI: / Copyright © 2007 The American Society of Human Genetics Terms and Conditions Terms and Conditions

Figure 1 The American Journal of Human Genetics , DOI: ( /513703) Copyright © 2007 The American Society of Human Genetics Terms and Conditions Terms and Conditions

Figure 2 The American Journal of Human Genetics , DOI: ( /513703) Copyright © 2007 The American Society of Human Genetics Terms and Conditions Terms and Conditions

Figure 3 The American Journal of Human Genetics , DOI: ( /513703) Copyright © 2007 The American Society of Human Genetics Terms and Conditions Terms and Conditions

Figure 4 The American Journal of Human Genetics , DOI: ( /513703) Copyright © 2007 The American Society of Human Genetics Terms and Conditions Terms and Conditions