Pawel Olko, IEEE meeting, The Henryk Niewodnicza ń ski Institute of Nuclear Physics Polish Academy of Sciences, IFJ PAN

Pawel Olko, IEEE meeting, History of the institute Pioneer measurements of cosmic rays, discovered the anisotropy of the viscosity in liquid crystals Prof. Marian Mięsowicz Prof. Henryk Niewodniczański ( ) Nuclear physicist, first director of IFJ

Pawel Olko, IEEE meeting, General information on IFJ PAN personnel (~190 with Ph.D.) - 17 departments / 5 divisions - centres of excellence - centres of advanced technology - accredited laboratories - technical sections - PhD studies (72 students)

Pawel Olko, IEEE meeting, Organigram of the IFJ PAN Prof. M.Jezabek General Director

Pawel Olko, IEEE meeting, Personnel

Pawel Olko, IEEE meeting, IFJ PAN Plans ( ) DESY –ZEUS/H1 CERN –ATLAS –LHCb KEKB ILC Pierre Auger Neutrinos –T2K –SUNLAB (Sieroszowice) Particle & Astroparticle Physics

Pawel Olko, IEEE meeting, IFJ PAN Plans ( ) RHIC CERN: –ALICE –ATLAS FAIR (GSI) SPIRAL2 (GANIL) Nuclear Physics & Strong Interactions

Pawel Olko, IEEE meeting, Nuclear Energy and Safety Nuclear technology & enviromental monitoring and dosimetry –Accredited Laboratories of:  Individual and Enviromental Dosimetry  Radiometric Expertise  Radioactivity Analysis –Education in collab. with AGH UST –High Temperature Reactor Thermonuclear energy –Stelarator WX7 (Greifswald) –ITER (neutron transport and cross section measurements)

Pawel Olko, IEEE meeting, Life Science Cluster in Kraków Radiobiology in IFJ PAN: –Van de Graaff accelerator: p microbeam –X microbeam –Isochronous cyclotron AIC-144 –NMR Imaging system Collaboration with JINR Dubna Proton radiotherapy projects –eye melanoma (firts patient 2009) – all localisations (2013)

Pawel Olko, IEEE meeting, Cyclotrons at IFJ PAN - first cyclotron in Poland developed by IFJ, 48 cm (1955) - classical cyclotron U-120 (opened , stopped 1994) -cyclotron isochronic AIC-144 (from 80’s) 59 MeV protons

Pawel Olko, IEEE meeting, Advantages of proton beam for cancer radiotherapy - well defined range of proton beam - small scattering - very precise irradiation

Pawel Olko, IEEE meeting, PROJECT OF THE PROTON OCULAR RADIOTHERAPY AT IFJ Eye melanoma - malignant tumor - proton therapy allows to save the eye globe and the useful vision - survival 95% -Clinic of Ophthalmology and Ophthalmic Oncology in Krakow treats 95% of ocular melanoma cases in Poland -Currently: surgery, laser, Ru-106 and I-125 brachytherapy new patients per year

Pawel Olko, IEEE meeting, Treatment room (year 2000) FACILITY Therapy room

Pawel Olko, IEEE meeting, The therapy room at IFJ Kraków

Pawel Olko, IEEE meeting, PROJECT OF THE PROTON OCULAR RADIOTHERAPY AT IFJ Timetable first proposal beginning of installation of AIC-144 cyclotron; construction of the treatment room; MeV proton beam delivered to treatment room; MeV proton beam delivered to the treatment room; purchasing of medical equipment and upgrading the AIC-144 cyclotron MeV proton beam, commissioning first patient

Pawel Olko, IEEE meeting, EU Structural Funds Division of Applied Physics and Interdisciplinary Research

Pawel Olko, IEEE meeting, EU Structural Funds Division of Applied Physics and Interdisciplinary Research

Pawel Olko, IEEE meeting, Consortium National Centre of Hadron Radiotherapy NCRH Grounded: IFJ PAN Kraków – coordinator Akademia Górniczo-Hutnicza Medical University, Warszawa, Center of Oncology, Warszawa Center of Oncology, Krakow Holycross Center of Oncology, Kielce Institute of Nuclear Problems, Warszawa Warsaw Polytechnic Silesia University Warsaw University

Pawel Olko, IEEE meeting, NCRH Phase I (Krakow) preliminarily approved Source: structural funds of EU for Poland IFJ has 10,000 m 2 of terrain for construction of new facility Timescale: Agreement signed with the Ministry of Science

Pawel Olko, IEEE meeting, For currently available funds: 1. Cyclotron ( MeV) 2. Energy selector 3. Beam transport 4. Bunker with the experimental hall 5. Eye-therapy room (moved from AIC-144) 6. Small laboratory building NCRH Phase I (Krakow) preliminarily approved From presentation of J. Heese, Varian -Accel

Pawel Olko, IEEE meeting, NCRH Phase I timetable Decision for the localization Announcement of the main tender Signing the contract Building permit Building completed Cyclotron operational

Pawel Olko, IEEE meeting, Installation of gantry for patient treatment  Gantry is rotating arm able to move the proton beam around the patient  Gantry allows for radiotherapy in arbitrary localization  Very good conformation of dose  The application for the installing gantry will be submitted Proton beam pacjent 11 metrów patient 11 meters

Pawel Olko, IEEE meeting, Final set-up with therapeutic gantry

Pawel Olko, IEEE meeting, Summary of proton radiotherapy 1.Eye melanoma proton radiotherapy starts at IFJ Krakow in May MeV proton beam will be delivered by AIC- 144 cyclotron. Cooperation with Clinic of Ophthalmology and Centre of Oncology 2.The project National Centre for Hadron Radiotherapy Phase 1 has been approved MeV cyclotron will be purchased, new cyclotron bunker and experimental hall will be constructed, eye treatment moved 3.The funds for the gantry have to be generated