What does EEG actually measure?

Slides:



Advertisements
Similar presentations
Note 2 Transmission Lines (Time Domain)
Advertisements

What are we measuring in EEG and MEG? Methods for Dummies 2007 Matthew Longo.
What are we measuring with
PHY132 Introduction to Physics II Class 12 – Outline:
BIOPOTENTIAL AMPLIFIERS
Electrophysiological approaches for examining “physiological” & “pathological” brain population (rhythmic) activities in rodent models Liang Zhang Toronto.
Basis of the M/EEG signal Evelyne Mercure & Bonnie Breining.
Induction and Alternating Current
Electrophysiology. Electroencephalography Electrical potential is usually measured at many sites on the head surface More is sometimes better.
What are we measuring with EEG and MEG James Kilner.
Electrophysiology.
Bioelectric Source Model and Brain Imaging Dezhong Yao School of Life Sci & Tech,UESTC.
Electrophysiology. Neurons are Electrical Remember that Neurons have electrically charged membranes they also rapidly discharge and recharge those membranes.
Opportunity to Participate
Subdural Grid Intracranial electrodes typically cannot be used in human studies It is possible to record from the cortical surface Subdural grid on surface.
Experimental Design in fMRI
Electroencephalography The field generated by a patch of cortex can be modeled as a single equivalent dipolar current source with some orientation (assumed.
Electroencephalography and the Event-Related Potential
The Event-Related Potential (ERP) We have an ERP waveform for every electrode.
Electroencephalography Electrical potential is usually measured at many sites on the head surface.
NEUR 4850 Advanced Techniques in Cognitive Neuroscience.
Dr. Jie ZouPHY Chapter 28 Direct Current Circuits.
An introduction to MEG Lecture 1 Matt Brookes.
Electric Current and Direct-Current Circuits
ELECTRICAL ENGINEERING: PRINCIPLES AND APPLICATIONS, Third Edition, by Allan R. Hambley, ©2005 Pearson Education, Inc. Chapter 14 Operational Amplifiers.
Storey: Electrical & Electronic Systems © Pearson Education Limited 2004 OHT 13.1 Capacitance and Electric Fields  Introduction  Capacitors and Capacitance.
Operational Amplifiers David Lomax Azeem Meruani Gautam Jadhav.
Closed and Open Electrical Fields
Chapter 27 Lecture 12: Circuits.
Chapter 18 Direct Current Circuits. Sources of emf The source that maintains the current in a closed circuit is called a source of emf Any devices that.
PHY-2049 Current & Circuits February ‘08. News Quiz Today Examination #2 is on Wednesday of next week (2/4/09) It covers potential, capacitors, resistors.
Lecture 13 Direct Current Circuits
Chapter 18 Direct Current Circuits. Sources of emf The source that maintains the current in a closed circuit is called a source of emf The source that.
Self-Inductance and Circuits LC circuits. 0 1τ 2τ 3τ 4τ 63% ε /R I t Recall: RC circuit, increasing current.
Chapter 25 Electric Circuits.
Electrical Energy and Potential IB Physics. Electric Fields and WORK In order to bring two like charges near each other work must be done. In order to.
Electric Potential AP Physics Chapter 17. Electric Charge and Electric Field 17.1 Electric Potential Energy and Potential Difference.
Introduction to Electrical Circuits Unit 17. Sources of emf  The source that maintains the current in a closed circuit is called a source of emf Any.
Chapter 28 Direct Current Circuits. Direct Current When the current in a circuit has a constant direction, the current is called direct current Most of.
INTRODUCTION The cell is the basic structural and functional unit of all living organism. It is the smallest unit of life, and is often called the building.
Electrostatics.
Electrical Energy and Potential
Electroencephalography Collecting and Analyzing Data: 101
Chapter 27: Circuits Introduction What are we going to talk about in chapter 28: What is an electromotive force ( E : emf)? What is the work done by an.
Circuits. In circuits, elements are connected by wires. Any connected region of wire has the same potential. (same color = same potential) The potential.
Chapter 27 Lecture 23: Circuits: I. Direct Current When the current in a circuit has a constant direction, the current is called direct current Most of.
Electric Potential: Charged Conductor
Cells and Batteries An electrical battery is one or more electrochemical cells that convert stored chemical energy into electrical energy Cells are portable.
Chapter 21 Electric Potential.
Mind Control of Systems Designing a system to measure brain waves in order to obtain commands to control the direction of a remote-control car By Gary.
Key Points Potential is Inversely Proportional to distance Electric Field Strength is Proportional to the Inverse Square of the distance Equipotentials.
ELECTROMOTIVE FORCE. Consider the following diagram showing a circuit with an external resistance (R) internal resistance (r) and EMF ( ε ). When.
1 Psychology 304: Brain and Behaviour Lecture 4. 2 Research Methods and The Structure of the Nervous System 2. What are the primary divisions of the nervous.
Circuit Electricity. Electric Circuits The continuous flow of electrons in a circuit is called current electricity. Circuits involve… –Energy source,
Electrophysiology. Neurons are Electrical Remember that Neurons have electrically charged membranes they also rapidly discharge and recharge those membranes.
Biomedical Instruments Design Biopotential Amplifiers
Baluns A balun is a type of transformer Used at RF
Analogue Electronic 2 EMT 212
Signals and systems By Dr. Amin Danial Asham.
Thevenin Theorem Any combination of batteries and resistances with two terminals can be replaced by a single voltage source e and a single series resistor.
Operational Amplifiers
What is an Op-Amp Low cost integrating circuit consisting of:
Electric Potential AP Physics Chapter 17.
Cycle 4 Methods Electrical Signals Dendritic membrane potentials
M/EEG Statistical Analysis & Source Localization
Electric Potential: Charged Conductor
Biomedical Instruments Design Biopotential Amplifiers 1.
Dynamic Causal Modelling for M/EEG
FIGURE 12-1 A Leyden jar can be used to store an electrical charge.
Basics of EEG recording
Presentation transcript:

What does EEG actually measure? The EEG What does EEG actually measure?

Neurons are Electrical Remember that Neurons have electrically charged membranes they also rapidly discharge and recharge those membranes (graded potentials and action potentials)

Electroencephalography pyramidal cells span layers of cortex and have parallel cell bodies their combined extracellular field is small but measurable at the scalp!

Whenever you build up charge in one place it tries to go somewhere else Voltage is a measure of the force with which charge tries to move

Electroencephalography pyramidal cells span layers of cortex and have parallel cell bodies their combined extracellular field is small but measurable at the scalp!

Electroencephalography Cell bodies and apical dendrites tend to be pointed in the same direction Perpendicular to the surface of the cortex

Electroencephalography The field generated by a patch of cortex can be modeled as a single equivalent dipolar current source with some orientation (assumed to be perpendicular to cortical surface) Duracell

The “forward solution” If we knew which parts of the brain were electrically active at a given time… And if we knew the orientation of the cortex at those points… And if we knew a few other parameters about the skull and scalp… We could figure out what the voltage would be at each point on the scalp! Duracell

The “inverse solution” EEG research at its essence is the process of running those steps in reverse Duracell

The “inverse solution” The first couple weeks of class will be spent running EEG “backwards” using the BESA dipole simulator We’ll make a hypothetical data set Then we’ll analyze it as if it were real Then we’ll collect real data and see how well they match Don’t get your hopes up…they won’t match all that well

Electricity made inaccurately simple: No such thing as voltage “at” a point Battery analogy – you can’t record voltage from a single end You always need a second point which we usually call a “ground” Why not use “ground” as ground? Potentially really dangerous! Totally unnecessary

Why not use “ground” as ground? Potentially really dangerous! Voltage would fluctuate wildly due to many other factors

A simple virtual ground circuit Use some other part of the head Basically that makes a really good receive antennae – picks up EVERYTHING! Noisy! Picks up radio frequency noise from many sources (outside the head

A differential circuit Also called “common-mode rejection” Also called “balanced line” Active electrode = V – 0 = V Notice what happens when external RF noise comes in – it gets “rejected” by the circuit (V + noise) – (0 + noise) = V – 0 = V Active – ground = V Reference – ground = “zero”

Common mode rejection works as long as the electrodes have the same electrical characteristics The most important of these is impedance We must ensure that the impedance of each electrode is low and consistent with the others

Choosing reference site Ideally it would be independent of brain electrical activity but that doesn’t really exist Instead we’ll compute a “virtual” reference that is the average of each of the electrodes