Gene expression Chapter 15 Genes and Development.

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Presentation transcript:

Gene expression Chapter 15 Genes and Development

Central dogma 1956 version of Central dogma by Francis Crick

Central dogma 1958 version of Central dogma

Genetic code

Transcription

DNA P’ase

RNA polymerase-3D at Online Macromolecular Museum

Transcription

RNA polymerase-3D at Online Macromolecular Museum

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. E1I1E2I2E3I3E4I4 Transcription Introns are removed Exons Introns Mature mRNA 3’ poly-A tail5’ cap 3’ poly-A tail Primary RNA transcript DNA template

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. E1I1E 2I 2E3I3E 4I 4 Transcription Introns are removed Intron Exon DNA a. b.c. Exons Introns mRNA Mature mRNA 3׳ poly-A tail 5׳ cap 3׳ poly-A tail Primary RNA transcript DNA template b: Courtesy of Dr. Bert O’Malley, Baylor College of Medicine

Translation

Genetic code

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