BIOC223 – FUNDAMENTALS OF BIOCHEMISTRY Carbohydrate Unit Objectives- Students will be able to C1. Collect/obtain biochemical information from a variety of credible sources about carbohydrates and present them using discipline appropriate representation. C2. Describe specific chemical and physical properties/ features of a carbohydrate and correlate elements of carbohydrate nomenclature and terminology with its structure. C3. Given the name or chemical formula of a carbohydrate, draw both the Fisher and Haworth representations of the carbohydrate and compare and contrast the two representations. C4. Given the structure of a carbohydrate identify functionally important chemical features and evaluate their roles in molecular recognition. C5. Given the structure of a carbohydrate identify the covalent bond that joins the monomer units and notate key features of the bond or macromolecule. C6. Given the structure of a carbohydrate predict the impact of chemical reactions and/or altering physical and chemical characteristics of the environment on the structure, physicochemical properties, and the function of the carbohydrate and evaluate their impact on molecular recognition. C7. Given the structure of a chemically modified carbohydrate, identify the chemical modifications and the modifying chemical reaction or given a specific chemical reaction create a modified carbohydrate. C8. Given the structures and functions of a variety of carbohydrates provide a chemical/mechanistic explanation to how carbohydrates perform a diversity of functions within biological systems by contextualizing specific structural features to explain specific functions. C9. Given the structure of a carbohydrate or a carbohydrate binding another compound/macromolecule, identify and analyze forces involved in intra- and inter-molecular interactions. C10. Given a figure and/or text depicting the key structural features of a macromolecular assembly involving carbohydrates, hypothesize forces stabilizing the structure and design an experimental test to evaluate the potential contributions of each force to stabilizing its structure. Overarching Objectives – Students will be able to O1. Find, analyze, discuss, and evaluate scientific content in a primary literature or scientific text that addresses a biochemical problem or claim O2. Demonstrate effective and productive teamwork O3. Communicate biochemical concepts to people within (peers and professor)and outside (public) the field.

WEEK7: First week of a two-week carbohydrates unit Reading (text book) 1 2 Concept Check: C1a, C2,C4 3 5 Worksheet 1a: O2, O3, C2, C4 4 Interactive lecture (new material) 6 Think-pair-share question: O2, O3, C2, C3 7 Wrap-up question: C2, C4 Worksheet 1b: O2, O3 C3, C6a Clicker Questions: C2-C7 Worksheet 2a: O2, O3, C7 Worksheet 2a: O2, O3, C6,C7 MCAT passage: O1, C5, C6 Think-pair-share question: O2, O3, C6, C8-10a Class Google Doc: O2, C1 Reading (Hidari et.al 2010) Interactive lecture (new material) Interactive lecture (based on Hidari 2010) 17 Worksheet 3: C8,C9,C10 18 Carbohydrate Assignment: Weis et. al, 1988 O1, O3, C1-C Student Work not assessment Individual assessment Participation/ Formative Professor Work not assessment Group assessment Participation/ Formative Individual assessment Low Stake/ Formative Individual assessment High Stake/ Summative in-class activities out-of-class activities TUE WED FRI MON THU SAT& SUN