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Presentation transcript:

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CANCER Cancer is not just one disease What is cancer? More than 200 different types of cancer have been identified CANCER

Defining cancer Cancer is an accumulation of abnormal cells that multiply through uncontrolled cell division and spread to other parts of the body by invasion and/or distant metastasis via the blood and lymphatic system Normal cells Abnormal cells Tumour growth Metastasis Uncontrolled cell division Invasion into surrounding tissues Spread via blood or lymphatic system

Incidence of cancer across the globe (2008, estimate)1 Evidence: Ferlay2008_CancerIncidenceContinent_GLOBOCAN, Ferlay2008_CancerIncidence2008_2030_GLOBOCAN 1. Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM. GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC Cancer Base No.10 [Internet]. Lyon, France: International Agency for Research on Cancer; 2010. Available from: http://globocan.iarc.fr, accessed on 06/06/2013.

Changing prevalence of cancer Global cancer incidence and mortality rates continue to rise1 25 M people living with cancer*2 75 M predicted to be living with cancer2 2030 21.3 M 2008 13.1 M GROWING AND AGEING POPULATION 12.7 M ADOPTION OF UNHEALTHY LIFESTYLES 7.6 M Evidence: Ferlay2008_CancerIncidence2008_2030_GLOBOCAN; Ferlay2008_CancerMortality2008_2030_GLOBOCAN; IARC 2008 (foreword; NB Cannot highlight relevant text). IMPROVEMENT IN DIAGNOSIS/SCREENING CASES DEATHS 2002 *Diagnosed in last 5 years 2030 Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM. GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC Cancer Base No.10 [Internet]. Lyon, France: International Agency for Research on Cancer; 2010. Available from: http://globocan.iarc.fr, accessed on 14/01/2013. The International Agency for Research on Cancer. World Cancer Report 2008. Available from: http://www.iarc.fr/en/publications/pdfs-online/wcr/, accessed on 06/06/2013.

Common cancers in men and women worldwide1 Evidence: CancerIncidenceInMenAndWomenByCancerType_GLOBOCAN 1. Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM. GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC Cancer Base No.10 [Internet]. Lyon, France: International Agency for Research on Cancer; 2010. Available from: http://globocan.iarc.fr, accessed on 06/06/2013.

Global cancer mortality Approximately 7.56 million people died from cancer in 2008,1 accounting for 13% of all deaths (from any cause)2 Lung, stomach, liver, colorectal and female breast cancers cause 50% of all cancer deaths1 Evidence: Ferlay2008_CancerMortalityInMenAndWomenByType_GLOBOCAN; AmericanCancerSociety_GlobalCancerFacts, table 1 (NB Cannot highlight) Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM. GLOBOCAN 2008 v2.0, Cancer Incidence and Mortality Worldwide: IARC Cancer Base No.10 [Internet]. Lyon, France: International Agency for Research on Cancer; 2010. Available from: http://globocan.iarc.fr, accessed on 06/06/2013. American Cancer Society. Global Cancer Facts and Figures 2nd Edition. Atlanta: American Cancer Society; 2011.