Transport of CO 2 Dissolved in plasma As bicarbonate ions As carbamino Hb or Carbamino Proteins Under normal resting conditions,an average of 4 ml of CO 2 is transported from tissues to lungs in each 100 ml of blood

Transport of CO2 in Dissolved state Accounts for 7% of all the CO 2 normally transported At PCO2 of venous blood 2.7 ml/dl At PCO2 of arterial blood 2.4 ml/dl i.e. 0.3 ml of CO 2 is transported in the form of dissolved CO 2 by each dl of blood

Transport as bicarbonate ions Accounts for 70% of CO2 transport from cells/ Tissues to lungs. CO2 + H2O H2 CO3 H + + HCO 3 H +Hgb HHgb Cl Cl Plasma

Transport as carbamino Hb Accounts for 23% of CO2 transport from cells to lungs CO2 + Hgb HgbCO2 Or CO2 +Plasma Proteins P.PCO2

Transport of CO 2

Haldane Effect Binding of oxygen of with hemoglobin tends to displace carbon dioxide from the blood or removing oxygen from hemoglobin increases the ability of Hb to pick up carbon dioxide and CO 2 - generated H.

Co 2 Dissociation Curve