(Internal Use)

Features of 7Days 1. The World’s first Registration of Neural Stem Cell as cosmetic ingredients by ICID. 2. Derived from neural stem cell 3. 80% of neural stem cell culture fluid  plenty of Growth factors & Peptides - KGF /EGF/IGF/PDGF/FGF/NGF/TGF - Glutathione - Argireline 4. Effect wrinkle : Argireline Whitening : Arbutin, Scutellaria root extract Rejuvenation : Growth Factors , Peptides

Large numbers culturing is possible from In vitro It is possible to produce “Homogeneous cell” from Single clone It is easy to introduce “Therapeutic genes” The protein that has strong regenerated function and can heal skin-injuries

It is possible to be differentiated to three main cells of CNS. (Neurons, Astrocytes, Oligodendrocytes) Epithelial growth factor(EGF) and fibroblast growth factor(FGF) are necessary in order to proliferate. It is equalized and easy to store and be cultivated.

Effectiveness of 7Days Serum Volume : 15ml (Whitening Serum) Scutellaria Root Extract ingredient intensively treats skin tone clearer and brighter by suppressing tyrosinase activity that is main cause of melasma and spots.   Volume : 15ml

Effectiveness of 7Days Emulsion Volume : 15ml (Wrinkle Repair Emulsion) Argireline (Acetyl Hexapeptide-3) derived from Stem Cell improve wrinkle which is formatted by contraction of muscle and recovery aged collagen and elastin. It is especially effective for fine line on the eye and lips area. Volume : 15ml

Effectiveness of 7Days Ceram (Intensive Lifting Cream) L-Cystine-2Hcl improve elasticity and renew skin by preventing skin acidification then increase in collagen. At the same time it Keeps skin in optimal moisture balance via constant hydration   Volume : 15ml

Main Ingredients Human Neural Cell Culture Extract Human Neural Cell Conditioned Media Defined Cell Culture Media 2 Scutellaria Root Extract Paeonia Extract Glycerin Arbutin Xanthan Gum Adenosine

Protein Analysis Content Name Growth factiors KGF /EGF/IGF/PDGF/FGF/NGF/TGF Adenylyl cyclase-associated protein IFP53 T-complex protein 1 FK506 binding protein 52 Keratin 10 ADCY1 Laminin-binding protein 26S proteasome subunit 11 Glyceraldehyde-3-phosphate dehydrogenase Tripeptide Glutathione Melanostatin Leupeptin Argireline

Argireline Acetyl Hexapeptide-3 (molecule) easy to permeate into skin as micro-peptide Function of Botox without side effects Intercept signal from motor nerves to muscle cells and control repetition for actions of wrinkles Regulates secretion of Catecholamines Increases skin-elasticity as regulating signal process of stem cells from wrinkle muscle Many cosmetics companies use this for anti-aging product

Comparison Argireline Botox Relaxes facial tension and reduce fine line & wrinkle highly effective in motion wrinkles cheaper expensive No pain and no tolerance Pain and Tolerance Not harmful occasionally leads to side effects Anyone can use requires physician-administered injections

Cause of Wrinkle Repeated contraction of muscle

Principle of Wrinkle Formation Synapse SNAP-25 Catecholamines (Neuraltransmitters) SNARE complex SNARE complex assembled

Working Process Botox Argireline SNARE Complex Broken SNARE Complex Destabilised

Epidermal Growth Factor The nature regenerated substance that is existed in human body The protein that has strong regenerated function and can heal skin-injuries Applications Cosmetics that can improve wrinkles and skin-power After epithelial peeling for beauty, it can regenerate normal skin

Fibroblast Growth Factor It is one of the growth factors that combined with Heparin to promote cells of Mesenchymal, Neuroectodermal and Endothelial origin It can cause cell-proliferation of various forms on In vitro It can accelerate growth of Fibroblasts, Myoblasts, Osteoblasts, Neuronal cells, Endothelial cells, Keratinocytes, Chondrocytes, and other cells. Cure degeneration of adult Vitiligo Cure injuries

Insulin-like growth factor It is very important factor to keep life. Its function is to regenerate damaged cells forming bones, muscles and nervous tissue Delaying hypophysis-aging It normalize blood sugar and insulin resistance

Platelet-derived growth factor Induce DNA synthesis Promote to combine Collagen with Protein Restrain apoptosis in Fibroblasts

Keratinocyte growth factor As an important medium for Hair growth, it can be affected to primary hair growth Involved to adhesion and increasing between cells Effective for curing and recovering injuries Involved to Epithelial repair

Protect cells from free radical Antioxidant Good for photo-aging (Dermatoheliosis) Acetyl Hexapeptide-3

It inhibits tyrosinase activity Effective for skin-whitening and prevent damage in skin as intercepting ultraviolet rays, active-oxygen As doing mycostasis and Anti-allergy, protect skins Antitumor action It is efficient on allergic disease and atopic dermatitis

Effect of SBG on Cell viability Results are expressed as a percent of viability relative to vehicle-treated controls. Effect of SBG on Melanogenesis in B16F1 cells

Influence of SBG on the tyrosinase activity and expression Effect of SBG on Melanogenesis in B16F1 cells

Date Registered Number Title Registered name of INCI 2009.04.10 1-04-2009-9803 NSP-1 Protein Complex from Neural Stem Cell 1-04-2009-9795 NSM-1 Human Neural Stem Cell Conditioned Media 4-04-2009-9805 ASM-1 Future CT's Modified Culture Medium   Future C .T in KOREA

Improvement : Whitening and red spots Age : 42 , Female Application : 7days Improvement : Whitening and red spots Before After 1 week

Improvement: black spots Age : 46, Male Application : 7 days Improvement: black spots Before After 3 week

Application : Tri-M (3sessions) +pepbu:w+7Days Age : 71 , Female Application : Tri-M (3sessions) +pepbu:w+7Days Improvement : deep wrinkle (eye area)and Lifting Before After 4weeks

Application : Tri-M (2 session) + Pepbu:w Age : 28 , Male Application : Tri-M (2 session) + Pepbu:w Improvement : Acne scar and Pore Before After 4weeks

Improvement : Whitening and Skin tone Age : 35 , Male Application : 7days Improvement : Whitening and Skin tone 100217 100303( 2Weeks)

Improvement : Whitening and Skin tone Age : 35 , Male Application : 7days Improvement : Whitening and Skin tone 100217 100303( 2Weeks)

How to use Pepbu:w Fractional laser / IPL + Pepbu:w Apply 2.5ml~5ml Pepbu:w immediately after laser and permiate it with cryo-electroporasion for cooling, penetrating of solution and regeneration Mesotherapy + Pepbu:w Apply Pepbu:w after making micro channel using therma stamp or Auto Stamp Needle(needle) and penetrate solution with cryo-electroporasion.

How to use 7Days Daily Use Laser/ Mesotherapy +7Days After making up skin balance using toner, apply evenly over face 2 or 3 drops of serum emulsion cream every morning and night time. Laser/ Mesotherapy +7Days Apply it after laser or needle treatment for regeneration of skin (home care)