Patient Presentation 22 year old female 22 year old female Sudden onset of severe, watery diarrhea Sudden onset of severe, watery diarrhea Nausea, vomiting Nausea, vomiting Physical exam: dry mouth, low blood pressure Physical exam: dry mouth, low blood pressure
You are the doctor, and you must save the patient’s life. Here is what you have to work with… Antiviral medication Antiviral medication Antibacterial medication (antibiotics) Antibacterial medication (antibiotics) Salt Salt Aspirin Aspirin Sugar Sugar Water Water Pepsi Pepsi
Skin Intestine Body
Skin Intestine Body Salt
Skin The Body Our Model System Conical Tube Dialysis Tube Intestine
Two Dialysis Tubes per Group Dialysis Tube Conical Tube Dialysis Tube
Two Dialysis Tubes per Group Conical Tube = water = sucrose
What happened to the dialysis tube with 80% sucrose? Why?
Sucrose Solution Water Osmosis
Osmosis Net Flow of Water
Sucrose Solution Net Flow of Water
How does your experiment explain cholera diarrhea?
Salt
Net Flow of Water
How would you treat the patient using osmosis?
Salt Sugar Salt Sugar Salt Sugar Salt Sugar
Salt Sugar Salt Sugar Salt Sugar Salt Sugar Salt Sugar Salt Sugar Salt Sugar Net Flow of Water