Breast Cancer

Dr. Swapna Chaudhary M.S. (MUM) M.S. (MUM) Consultant Obstetrician & Gynaecologist Infertility Specialist

Incidence

Incidence  Common cause of cancer in females

Incidence  200,000 new cases annually around world

Incidence  Common cause of cancer in females  200,000 new cases annually around world  40,000 deaths

Risk Factors

 Age > 50

Risk Factors  Age > 50  High income group

Risk Factors  Age > 50  High income group  Family History (mother / sister)

Risk Factors  Age > 50  High income group  Family History (mother / sister) (Risk increases if > 1 1 st degree relative affected, bilateral breast disease, young age at diagnosis) (Risk increases if > 1 1 st degree relative affected, bilateral breast disease, young age at diagnosis)

Risk Factors  Age > 50  High income group  Family History (mother / sister) (Risk increases if > 1 1 st degree relative affected, bilateral breast disease, young age at diagnosis) (Risk increases if > 1 1 st degree relative affected, bilateral breast disease, young age at diagnosis)  BRCA mutation

Risk Factors  Age > 50  High income group  Family History (mother / sister) (Risk increases if > 1 1 st degree relative affected, bilateral breast disease, young age at diagnosis) (Risk increases if > 1 1 st degree relative affected, bilateral breast disease, young age at diagnosis)  BRCA mutation  Nulliparity (no children)

 1 st pregnancy after 30 yrs

 Early menarche

 1 st pregnancy after 30 yrs  Early menarche  Late menopause

 1 st pregnancy after 30 yrs  Early menarche  Late menopause  Obesity

 1 st pregnancy after 30 yrs  Early menarche  Late menopause  Obesity  Poss. Risk factors – high dietary fat, prolonged use of OCP (>10 yrs), alcohol, stress

Screening methods

1.Breast self examination

Screening methods 1.Breast self examination 2.Clinical examination

Screening methods 1.Breast self examination 2.Clinical examination 3.Mammography

Screening methods 1.Breast self examination 2.Clinical examination 3.Mammography  screening method – done for non palpable, early, small (<1cm) tumors in asymptomatic women

Screening methods 1.Breast self examination 2.Clinical examination 3.Mammography  screening method – done for non palpable, early, small (<1cm) tumors in asymptomatic women  ‘abnormal mass’ further investigated by additional imaging or biopsy

 Screening mammography can detect cancer 2 to 3 yrs before it can become symptomatic (10% cancer still failed to be detected by mammography)

4. FNAC / biopsy

Treatment

Treatment  Surgical Treatment

Treatment  Mastectomy

Treatment  Surgical Treatment  Mastectomy  Breast conservation

Treatment  Surgical Treatment  Mastectomy  Breast conservation  Lumpectomy with XRT

Treatment  Surgical Treatment  Mastectomy  Breast conservation  Lumpectomy with XRT  Equal outcomes!

Thank you