v SCF Ras GDP Inactive nucleus SCF Ras GDP Inactive nucleus.

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Presentation transcript:

v SCF Ras GDP Inactive nucleus

SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

v SCF Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus

Ras GDP Inactive nucleus P P P P

P P P P Ras GDP Inactive Active ! nucleus

P P P P Ras GDP Inactive Active ! nucleus

P P P P Ras GDP Inactive Active ! nucleus

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src

P P P P Ras GDP Inactive nucleus Src P

P P P P Ras GDP Inactive nucleus Src P Active!

P P P P Ras GDP Inactive nucleus Src P Active!

P P P P Ras GDP Inactive nucleus Src P Active!

P P P P Ras GDP Inactive nucleus Src P Shc

P P P P Ras GDP Inactive nucleus Src P Shc

P P P P Ras GDP Inactive nucleus Src P Shc

P P P P Ras GDP Inactive nucleus Src P Shc

P P P P Ras GDP Inactive nucleus Src P Shc

P P P P Ras GDP Inactive nucleus Src P Shc

P P P P Ras GDP Inactive nucleus Src P Shc

P P P P Ras GDP Inactive nucleus Src P Shc

P P P P Ras GDP Inactive nucleus Src P Shc

P P P P Ras GDP Inactive nucleus Src P Shc

P P P P Ras GDP Inactive nucleus Src P Shc

P P P P Ras GDP Inactive nucleus Src P Shc P

P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

GTP P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

GTP P P P P Ras GDP Inactive nucleus Src P Shc P Grb2 Sos

Ras GDPGTP P P P P Ras Inactive nucleus Src P Shc P Grb2 Sos

Ras GDP GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos

Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Active!

Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Active! Inactive Raf-1

Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Active! Raf-1

MEK Inactive Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1

MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 Inactive

MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 Inactive P

MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 Active! P

MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 Active! P

Erk MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 Active! P Inactive

Erk MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 Active! P Inactive

Erk MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 P Inactive

Erk MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 P Inactive

Erk MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 P Inactive

Erk MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 P Inactive PPPP

Erk MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 P Active! PPPP

MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 P Erk PPPP

MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 P Erk PPPP

MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 P Erk PPPP

PPPP MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 P

Erk PPPP MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 P

Erk PPPP MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 P

Erk PPPP MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 P

Erk PPPP MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 P

Erk PPPP MEK Ras GTP Ras GTP P P P P Ras nucleus Src P Shc P Grb2 Sos Raf-1 P

Erk PPPP MEK Ras GTP Ras GTP P P P P Ras Src P Shc P Grb2 Sos Raf-1 P Transcription!

Erk PPPP MEK Ras GTP Ras GTP P P P P Ras Src P Shc P Grb2 Sos Raf-1 P Transcription! cell growth

Erk PPPP MEK Ras GTP Ras GTP P P P P Ras Src P Shc P Grb2 Sos Raf-1 P Transcription! cell growth

Erk PPPP MEK Ras GTP Ras GTP P P P P Ras Src P Shc P Grb2 Sos Raf-1 P Transcription! cell growth

Erk PPPP MEK Ras GTP Ras GTP P P P P Ras Src P Shc P Grb2 Sos Raf-1 P Transcription! cell growth