CTCF: the protein, the binding partners, the binding sites and their chromatin loops by Sjoerd Johannes Bastiaan Holwerda, and Wouter de Laat Philosophical.

Slides:



Advertisements
Similar presentations
Closing yield gaps: perils and possibilities for biodiversity conservation by Ben Phalan, Rhys Green, and Andrew Balmford Philosophical Transactions B.
Advertisements

Effects of acidification on olfactory-mediated behaviour in freshwater and marine ecosystems: a synthesis by Antoine O. H. C. Leduc, Philip L. Munday,
Black-box calibration for complex-system simulation by Alexander I. J. Forrester Philosophical Transactions A Volume 368(1924): August 13, 2010.
STRATEGY FOR GENE REGULATION 1.INFORMATION IN NUCLEIC ACID – CIS ELEMENT CIS = NEXT TO; ACTS ONLY ON THAT MOLECULE 2.TRANS FACTOR (USUALLY A PROTEIN) BINDS.
Current Topics of Genomics and Epigenomics. Outline  Motivation for analysis of higher order chromatin structure  Methods for studying long range chromatin.
Unusual co-crystal of isonicotinamide: the structural landscape in crystal engineering by Srinu Tothadi, and Gautam R. Desiraju Philosophical Transactions.
Energy, ageing, fidelity and sex: oocyte mitochondrial DNA as a protected genetic template by Wilson B. M. de Paula, Cathy H. Lucas, Ahmed-Noor A. Agip,
Molecular genetics of gene expression Mat Halter and Neal Stewart 2014.
Magnetic flux emergence and associated dynamic phenomena in the Sun by Vasilis Archontis Philosophical Transactions A Volume 370(1970): July 13,
Charge storage mechanism in nanoporous carbons and its consequence for electrical double layer capacitors by Patrice Simon, and Yury Gogotsi Philosophical.
Using high-resolution displays for high-resolution cardiac data by Christopher Goodyer, John Hodrien, Jason Wood, Peter Kohl, and Ken Brodlie Philosophical.
An Introduction to ENCODE Mark Reimers, VIPBG (borrowing heavily from John Stamatoyannopoulos and the ENCODE papers)
Flexible services for the support of research by Matteo Turilli, David Wallom, Chris Williams, Steve Gough, Neal Curran, Richard Tarrant, Dan Bretherton,
Reduced-order models for nonlinear vibrations, based on natural modes: the case of the circular cylindrical shell by Marco Amabili Philosophical Transactions.
Bionics in textiles: flexible and translucent thermal insulations for solar thermal applications by Thomas Stegmaier, Michael Linke, and Heinrich Planck.
The formation and control of emerging disinfection by- products of health concern by Stuart W. Krasner Philosophical Transactions A Volume 367(1904):
Carbon neutral hydrocarbons by Frank S Zeman, and David W Keith Philosophical Transactions A Volume 366(1882): November 13, 2008 ©2008 by The.
Subject-specific, multiscale simulation of electrophysiology: a software pipeline for image-based models and application examples by R.S. MacLeod, J.G.
Systematic identification of 3′-UTR regulatory elements in activity-dependent mRNA stability in hippocampal neurons by Jonathan E. Cohen, Philip R. Lee,
Emiliania huxleyi increases calcification but not expression of calcification-related genes in long-term exposure to elevated temperature and pCO 2 by.
Sector and Sphere: the design and implementation of a high-performance data cloud by Yunhong Gu, and Robert L. Grossman Philosophical Transactions A Volume.
Key challenges in future Li-battery research by J.-M. Tarascon Philosophical Transactions A Volume 368(1923): July 28, 2010 ©2010 by The Royal.
Stochastic two-delay differential model of delayed visual feedback effects on postural dynamics by Jason Boulet, Ramesh Balasubramaniam, Andreas Daffertshofer,
Rinderpest: the veterinary perspective on eradication by Peter Roeder, Jeffrey Mariner, and Richard Kock Philosophical Transactions B Volume 368(1623):
Thermodynamics of surface degradation, self-organization and self-healing for biomimetic surfaces by Michael Nosonovsky, and Bharat Bhushan Philosophical.
A fast-evolving human NPAS3 enhancer gained reporter expression in the developing forebrain of transgenic mice by Gretel B. Kamm, Rodrigo López-Leal, Juan.
Two underestimated threats in food transportation: mould and acceleration by S. Janssen, I. Pankoke, K. Klus, K. Schmitt, U. Stephan, and J. Wöllenstein.
Past, present and impendent hydroelastic challenges in the polar and subpolar seas by Vernon A. Squire Philosophical Transactions A Volume 369(1947):
Spectroscopic measurement of the vapour pressure of ice by K. Bielska, D. K. Havey, G. E. Scace, D. Lisak, and J. T. Hodges Philosophical Transactions.
Surface science investigations of the role of CO 2 in astrophysical ices by John L. Edridge, Kati Freimann, Daren J. Burke, and Wendy A. Brown Philosophical.
Hydrogen: the future energy carrier by Andreas Züttel, Arndt Remhof, Andreas Borgschulte, and Oliver Friedrichs Philosophical Transactions A Volume 368(1923):
Theory of hybrid dynamical systems and its applications to biological and medical systems by Kazuyuki Aihara, and Hideyuki Suzuki Philosophical Transactions.
Towards elucidation of dynamic structural changes of plant thylakoid architecture by Jan M. Anderson, Peter Horton, Eun-Ha Kim, and Wah Soon Chow Philosophical.
Reframing the climate change challenge in light of post emission trends by Kevin Anderson, and Alice Bows Philosophical Transactions A Volume 366(1882):
Cumulative carbon as a policy framework for achieving climate stabilization by H. Damon Matthews, Susan Solomon, and Raymond Pierrehumbert Philosophical.
Hydrocarbon liquefaction: viability as a peak oil mitigation strategy by Mikael Höök, Dean Fantazzini, André Angelantoni, and Simon Snowden Philosophical.
Metal chalcogenide nanoclusters with ‘tailored’ surfaces via ‘designer’ silylated chalcogen reagents by Daniel G. MacDonald, and John F. Corrigan Philosophical.
Climate change effects on above- and below-ground interactions in a dryland ecosystem by Adela González-Megías, and Rosa Menéndez Philosophical Transactions.
Raman spectroscopy of volcanic lavas and inclusions of relevance to astrobiological exploration by Susana E. Jorge-Villar, and Howell G. M. Edwards Philosophical.
Materials towards carbon-free, emission-free and oil-free mobility: hydrogen fuel-cell vehicles—now and in the future by Katsuhiko Hirose Philosophical.
Philosophical Transactions B
Structure-aided prediction of mammalian transcription factor complexes in conserved non-coding elements by Harendra Guturu, Andrew C. Doxey, Aaron M. Wenger,
Requirements of the cytosolic iron–sulfur cluster assembly pathway in Arabidopsis by Delphine G. Bernard, Daili J. A. Netz, Thibaut J. Lagny, Antonio J.
Projecting cell polarity into the next decade by Attila Csikász-Nagy, Masamitsu Sato, and Rafael E. Carazo Salas Philosophical Transactions B Volume 368(1629):
Molecular evolutionary signatures reveal the role of host ecological dynamics in viral disease emergence and spread by Scott M. Duke-Sylvester, Roman Biek,
Modelling heat transfer in heterogeneous media using fractional calculus by Dominik Sierociuk, Andrzej Dzieliński, Grzegorz Sarwas, Ivo Petras, Igor Podlubny,
Evolutionary analysis of hepatitis C virus gene sequences from 1953 by Rebecca R. Gray, Yasuhito Tanaka, Yutaka Takebe, Gkikas Magiorkinis, Zelma Buskell,
Elena Klenova CTCF and BORIS in normal development, epigenetics and tumourigenesis Areas of research: Molecular Oncology Gene regulation Translational.
Control of Gene Expression
Functional Mapping and Annotation of GWAS: FUMA
Genome Organization: Cohesin on the Move
Can We Just Say: Transcription Second?
Transcriptional Memory: Staying in the Loop
Regulation of transcription: from lambda to eukaryotes
Approaching TERRA Firma: Genomic Functions of Telomeric Noncoding RNA
Control of Gene Expression in Eukaryotic cells
A CTCF Code for 3D Genome Architecture
Dale Dorsett, Lena Ström  Current Biology 
Genetic variation in DREs could be a causative factor in dysregulation of distal target gene expression. Genetic variation in DREs could be a causative.
Transcriptional Addiction in Cancer
Control of Gene Expression in Eukaryotic cells
Osteoarthritis year 2013 in review: genetics and genomics
Proteins Kinases: Chromatin-Associated Enzymes?
Prokaryotic (Bacterial) Gene Regulation
Genome Organization: Cohesin on the Move
CTCF Binding Polarity Determines Chromatin Looping
A Role for Epigenetics in Psoriasis: Methylated Cytosine–Guanine Sites Differentiate Lesional from Nonlesional Skin and from Normal Skin  Johann E. Gudjonsson,
Denes Hnisz, Daniel S. Day, Richard A. Young  Cell 
A New Cohesive Team to Mediate DNA Looping
Transcriptional control: Imprinting insulation
Presentation transcript:

CTCF: the protein, the binding partners, the binding sites and their chromatin loops by Sjoerd Johannes Bastiaan Holwerda, and Wouter de Laat Philosophical Transactions B Volume 368(1620): June 19, 2013 ©2013 by The Royal Society

CTCF, chromatin loops and transcription regulation at selected gene loci. Sjoerd Johannes Bastiaan Holwerda, and Wouter de Laat Phil. Trans. R. Soc. B 2013;368: ©2013 by The Royal Society

A versatile role for CTCF in chromatin biology. Sjoerd Johannes Bastiaan Holwerda, and Wouter de Laat Phil. Trans. R. Soc. B 2013;368: ©2013 by The Royal Society

CTCF acts as an insulator by hampering DNA contacts across its binding sites. Sjoerd Johannes Bastiaan Holwerda, and Wouter de Laat Phil. Trans. R. Soc. B 2013;368: ©2013 by The Royal Society