Allergies in America: A Landmark Survey of Nasal Allergy Sufferers Executive Summary Conducted by Schulman, Ronca & Bucuvalas, Inc. February 17, 2006 Supported by:

1 Study Design PopulationSampling FrameInterview Length Completed Sample Population Aged 18+National RDD34.8 minutes2,500 Cross-section: 1/4/06-1/31/06 Health Professionals Doctors -- Adult Primary Care -- Allergy -- Otolaryngology Nurse practitioners Physician assistants AMA/AOA Master List: Licensing Boards American Academy of Physician Assistants 19.4 minutes Physician Survey: 1/17/06-2/14/06

2 Adults Diagnosed with Nasal Allergies: Household Screening QA. Including yourself, how many persons, aged 18 and older, live in this household (even if they are not there right now)? QB. Have any of these persons been diagnosed as having hay fever, rhinitis, or nasal allergies? QC. How many persons, 18 or older, in this household have been diagnosed with hay fever, rhinitis or nasal allergies? N=61,655 adults in 31,470 households

3 Seasonal or Persistent Allergies Q12.Would you describe your nasal allergies as seasonal or do they occur throughout the year? N=2,500

4 Symptoms During Worst Month Q14. During the worst one month period in the past year, did you have (symptom) every day, most days a week, a few days a week, a few days a month, less than that, or never? Unweighted N=2,500

5 How Bothersome are Symptoms Q15. When you have nasal allergy attacks, how bothersome are the following symptoms usually --- extremely bothersome, moderately bothersome, slightly bothersome, or not bothersome? N=2,500

6 Most Bothersome Symptom Q16. Which of these symptoms was the most bothersome to you? Base: Had bothersome symptoms N=2,362

7 Degree of Discomfort from Allergies Q17. In general, when you have a nasal allergy attack would you say that your discomfort is usually something you can ignore, you can’t ignore it, but you can tolerate it, or you can’t tolerate it without relief? N=2,500

8 Symptoms During Worst Month Q30.During allergy season, how often do you feel (ITEM) – frequently, sometimes, rarely or never? N=2,500

9 Impact of Allergies on Daily Life Q31. During allergy season, would you say the condition impacted your daily life …..? N=2,500

10 Work Interference from Nasal Allergies Q22a.Have you missed work in the past 12 months due to your nasal allergies? Q23a. Aside from actually missing work, have your nasal allergy symptoms in the past 12 months interfered with your performance at work? Base: Employed full time N=1,315

11 Productivity and Allergies Q24. Thinking about your productivity on a scale of 0 to 100, where 100 means 100% productivity, where would your rank your productivity on days when you don’t have nasal allergy symptoms? Q25. Where would you rank your productivity on the same scale of 0 to 100 … when your nasal allergies are at their worst? Base: Employed full time N=1,315 Mean Productivity

12 Seen Doctor for Nasal Allergies in Past 12 Months by Symptom Severity Q42a.Have you seen a health practitioner about your nasal allergies in the past 12 months? Q33. How would you describe your nasal allergy symptoms during the last week? Would you say that you had no symptoms, mild symptoms, moderate symptoms or severe symptoms? N =2,500

13 Medicine for Allergies in Past 4 Weeks Q63a.In the past 4 weeks, have you used any over-the-counter, non-prescription medicine to give you relief from nasal allergy symptoms? Q63b. When was the most recent time that you used an over the counter, non- prescription medicine for relief from nasal allergy symptoms? Q64a. In the past 4 weeks, have you used any prescription nasal spray for your nasal allergies? Q64b. When was the most recent time that you used a prescription nasal spray for your nasal allergies? Q72a. Have you taken any other prescription medications for your nasal allergies in the past 4 weeks? N=2,500

14 Satisfaction with Recent Rx Nasal Spray for Nasal Allergies Q63f. How satisfied are you with the over-the-counter medicine you used for your nasal allergies in the past 4 weeks? Q70a. How satisfied are you with the prescription nasal spray you used for your nasal allergies in the past 4 weeks? Q78. How satisfied are you with the other prescription medicine you used for your nasal allergies in the past 4 weeks?

15 How Many Symptoms Relieved by Nasal Spray Q65. Does your current prescription nasal spray give you relief from all of your symptoms, most symptoms, some symptoms, or no symptoms? Base: Use prescription nasal spray. N=919

16 How Quickly Does it Relieve Q68. How long does it take for your current prescription nasal spray to begin giving you symptom relief? Base: Use prescription nasal spray N=919

17 Does Effectiveness Wear Off Q69a. Does your current prescription nasal spray lose effectiveness over the course of the day or night, or does it remain as effective as when you first took it? Base: Use prescription nasal spray N=919

18 When Begins Losing Effectiveness Q69b. How long after taking your current nasal allergy medicine does it begin losing effectiveness? Base: Nasal spray loses effectiveness N=440

19 Change Prescription Medicines for Nasal Allergies Q81a.How often do you change nasal allergy medicines ---several times each year, once a year, every few years, only rarely or never? N=2,500

20 Why Changed Medicine for Nasal Allergies Q81b.Why have you changed nasal allergy medicines? Anything else? Base: Have changed nasal allergy medicines N=1,723

21 Asked Doctor to Change Medication Q82a.Have you ever asked your doctor to change your nasal allergy medication because you were dissatisfied with it? N=2,500

22 Why Dissatisfied with Nasal Allergy Medicine Q82c. Why were you dissatisfied with that medicine? Base: Have asked doctor to change nasal allergy medicines N=860

23 Effectiveness Ever Wore Off before 24 Hours Q87a. Have you ever found that the effectiveness of a product that promised 24 hour relief began wearing off earlier? N=2,500

24 When Does Effectiveness Wear Off Q87c. About how long after you started taking it does a nasal allergy medicine’s effectiveness begin wearing off? Base: Found nasal allergy medicine offering 24 hour relief wearing off N=1,461

25 Stopped Taking Because Effectiveness Wore Off Q87d. Have you ever stopped taking a product for your nasal allergies because its effectiveness had worn off?

26 Effectiveness Wears Off Over Time Q88a. Have you ever found that a product’s effectiveness in treating your nasal allergy symptoms wears off over time even when you are taking the medicine as prescribed? Q88b. Has this happened to you with more than one nasal allergy product? N=2,500

27 When Does Effectiveness Wear Off Q88c. About how long after you started taking it does a nasal allergy medicine’s effectiveness begin wearing off even when taken as prescribed? Base: Found nasal allergy medicine wearing off N=1,364

28 Stopped Taking Because Effectiveness Wore Off Q88d. Have you ever stopped taking a product for your nasal allergies because its effectiveness had worn off?

29 Side Effects of Allergy Medicines Q90.How many of the medicines that you have taken for allergy had the following types of side effects --- all, most, some, few or none? N=2,500

30 How Bothersome are Side Effects Q91. How bothersome are the following side effects of nasal allergy medicines --- extremely, moderately, slightly or not bothersome? N=2,500

31 Reason Stopped Taking Nasal Allergy Prescription Q94.Have you ever stopped taking a nasal allergy medicine prescribed by your doctor because…. N=2,500

32 How often Patients Follow Advice Q19. Would you say that most of your patients with allergic rhinitis follow your advice on the management and treatment of nasal allergies…? N=400 PQ49. Would you say that you follow your health practitioner’s advice on the management and treatment of your nasal allergies – all of the time, most of the time, some of the time, rarely or never? N=2,500

33 Failed to Follow Physician Instructions Q108. People with nasal allergies sometimes fail to follow their physician’s instructions about their medicines for allergies. Have you ever failed to take an allergy medicine as prescribed because of …… N=2,500

34 Important for Nasal Allergy Medicine Q98. In choosing a nasal allergy medicine, which would be the most important to you …? Q99. What would be the next most important to you? N=2,500

35 Discomfort During Allergy Attack Q8. In general, would you say that patients’ discomfort during a nasal allergy attack is usually something they can ignore, they can’t ignore it, but they can tolerate it, or they can’t tolerate it without relief? N=400 PQ17. In general, when you have a nasal allergy attack would you say that your discomfort is usually something you can ignore, you can’t ignore it, but you can tolerate it, or you can’t tolerate it without relief? N=2,500

36 Productivity when Nasal Allergies are at Their Worst Q10. Thinking about productivity at work on a scale from 0 to 100, where 100 means 100% productivity, where would you rank the productivity of persons with allergic rhinitis, when their nasal allergies are at their worst? N=400 PQ25. Where would you rank your productivity on the same scale of 0 to 100 … when your nasal allergies are at their worst? Base: Employed full time N=1,315

37 Percent of Patients Very Satisfied With Disease Management Q20. Approximately, what proportion of your patients with nasal allergies would you say are VERY satisfied with the management of their disease? Would you say… N=400 PQ51. Overall, how satisfied are you with your health practitioner’s management and treatment of your nasal allergies? N=2,500

38 Satisfaction of Patients with Intra- nasal Corticosteroids Q36.In general, how satisfied are your allergic rhinitis patients with their intra-nasal corticosteroids? Would you say that they are very satisfied, somewhat satisfied, somewhat dissatisfied, or very dissatisfied? N=400 PQ70b. In general, how satisfied have you been with the prescription nasal spray you have used for your nasal allergies in the past? Base: Ever used Rx nasal spray for nasal allergies N=2,033

39 Patients Get Monies Worth from Rx Medicines Q30.Overall, do your patients feel they get their money’s worth out of prescription medicines for nasal allergies? N=400 PQ97. Overall, do you feel that patients get their money’s worth out of prescription medicines for nasal allergies? N=2,500

40 Opinions About Nasal Allergies Q44. Now I am going to read you a series of statements. As I read each statement, please tell me whether you agree strongly, agree somewhat, disagree somewhat or disagree strongly with the statement. N=400 PQ110. Now I am going to read you a series of statements. As I read each statement, please tell me whether you agree strongly, agree somewhat, disagree somewhat or disagree strongly with the statement N=2,500

41 Need for Better Education of Patients Q45. How much need do you think there is for better education of PEOPLE WITH NASAL ALLERGIES about their condition and its treatment? Do you think there is a… N=400 PQ113. How much need do you think there is for better education of people with nasal allergies about their condition and its treatment? N=2,500

42 Aware of Professional Guidelines Q46a. Are you aware of any professional guidelines for the diagnosis and management of allergic rhinitis? N=400

43 Publisher of Guidelines Q46b. Who publishes those guidelines? Base: Aware of Guidelines N=260