BIO-FREQUENCY SPECTRUM RADIATION & WOUND HEALING

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Presentation transcript:

BIO-FREQUENCY SPECTRUM RADIATION & WOUND HEALING J. M. Schramm, M.A., R. A. Hardesty, M.D., K. C. Oberg, M.D., Ph.D.

BFS & WOUND HEALING PROBLEM & BACKGROUND GOALS & OBJECTIVES METHODS RESULTS DISCUSSION CONCLUSIONS

CLINICAL PROBLEM Compromised wound healing (bed sores, DM, smokers) Electromagnetic radiation in wound healing Microwave radiation in wound healing Infrared radiation in wound healing Bio-Frequency Spectrum (BFS) radiation

BACKGROUND: BFS & LIGHT SPECTRUM Light frequency spectrum Microwave Infrared BFS

BACKGROUND: BFS RADIATION TREATMENT Reported results of BFS treatment for bed sores Reported results from C. Kun, et. al., 1995.

GOALS & OBJECTIVES Controlled evaluation of wound healing MacFarlane flap tissue survival Simple incision breaking strength

METHODS: EXPERIMENTAL TECHNIQUES Anesthesia Nembutal 2 cc/kg Flap design MacFarlane flap Standardization 4x10 cm template Stapled incision

METHODS: EXPERIMENTAL TECHNIQUES Anesthesia Nembutal 2 cc/kg Incisional design Midline incision Standardization 3 cm template Clipped incision

METHODS: TREATMENT PROTOCOL Control group No treatment (Social cage 30 min. twice daily)

METHODS: TREATMENT PROTOCOL Treatment groups Infrared radiation 30 min. twice daily BFS radiation 30 min. twice daily

RESULTS: DATA ANALYSIS MacFarlane flap Planimetric analysis Surface area survivability

RESULTS: DATA ANALYSIS Simple incision Tensiometer analysis Wound breaking strength

RESULTS: MACFARLANE FLAP BFS treatment 22.0% (+/- 11.8%) p<.01 vs. controls p=.16 vs. IR IR treatment 30.3% (+/- 10.0%) Controls 36.9% (+/- 9.6%)

RESULTS: SIMPLE INCISION BFS treatment 2.62N/mm2(+/-0.44N/mm2) p<.001 vs. controls p<.10 vs. IR IR treatment 2.26N/mm2(+/-0.38N/mm2) p<.03 vs. controls Controls 1.73N/mm2(+/-0.47N/mm2)

DISCUSSION BFS vs. Controls BFS vs. IR Less flap necrosis Greater wound breaking strength p<.001 BFS vs. IR Trend towards less flap necrosis p=.16

CONCLUSIONS BFS as efficient as IR in wound healing BFS trends Flap necrosis Simple incision tensile strength BFS trends Appears to show greater wound healing than IR Future research Verify results Expand to other models

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