Asthma Medication Adherence for Children

Owen 2

Asthma 3

10M CHILDREN $15B IN COSTS 50% PREVENTABLE Asthma In the US 4

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Main Existing Barriers Adherence < 40% 6

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US Children’s Asthma 10M Children $15B WORLDWIDE 300M People With Respiratory Diseases * US Total Asthma + COPD 40M People $100B Respiratory Diseases: Market Opportunity * Additional 100M people with asthma worldwide by

The Adherence Problem = $317B in US ADHD Anemia Cancer Dermatology Diabetes IBD Mental Health * Express Scripts: “$317B in excess health costs, 69% due to procrastination and forgetfulness” 10 US CHRONIC PEDI MEDICATION

Evolution of a m.Health startup in 2013: Gamification as a way to motivate people How to be the best asthma consumer product Design, UX, and UI Who is our real customer? ACO, a “great opportunity” for connected device coverage? 11 The Beginning

Gamification as a way to motivate people

How to be the best asthma consumer product (and stay away from healthcare) 13

14 Design, UX, and UI Really Matter

Who is our real customer? Kids (users & beneficiaries) Doctors (“trail guides”) Parents (users & beneficiaries) Friends Other Caregivers Parents of other kids with G.C. Other kids with G.C. Pharmacy/PBM (sellers) Pharma (inhaler providers) Data customers 1 15

ACO, a “great opportunity” for connected device reimbursement ? 16

Evolution of a m.Health Startup in 2013: This is what bothers us NOW Clinically proven mobile products? What is the meaning of meaningful use of data? FDA / HIPPA / Privacy? What do risk holders want? Reimbursement process and CMS Coding for apps and mobile devices? 17

Clinically Proven, Self Managed Grants for non-regulated mobile apps RCT for mobile products Hard to measure: what are the expected outcomes? What is our place in the clinical workflow? 18

Meaningful Use of Data How do you show more than just what you measure? What will make a difference? How do you make the UX “one” with the user’s lifestyle? 19

FDA, FCC, CMS, ONC OLD regulations for NEW Solutions FDA regulations for mobile applications Privacy: who handles all the healthcare data in the cloud? Vs 20

What Do Risk Holders Want? Payers? PBMS? Drug manufacturers? How should we prove ROI, show clinical evidence, reduce costs? What can we sell? Hardware, Software, Data? Who will pay: Consumers Pharma, PBMs Pharma, PBMs Payers, Providers 21

HSPCS, NDC, UDI, CPT, DRG, &%$# New Solutions – Old Payment Systems Reimbursement process and Coding CMS Accountable Care payment system? 22

@engelhardy 23