Grand Rounds Peripheral Exudative Hemorrhagic Chorioretinopathy

Slides:



Advertisements
Similar presentations
Overview Of Retinal Conditions Clinical and OCT Findings Central Coast Day Hospital Inaugural Optometrist Conference 26th February 2012 Anil Arora.
Advertisements

Grand Rounds Conference
1 ICD-9-CM Coordination and Maintenance Committee Meeting October 8 th, 2004 Matthew J. Sheetz, MD, PhD Promoting Clear Identification of Diabetic Retinopathy.
Evan (Jake) Waxman MD PhD
Retinal Imaging Conference Eddie Apenbrinck MD University of Louisville School of Medicine Department of Ophthalmology & Visual Sciences 1/23/14.
GH.Naderian, M.D.. Supra choroidal hemorrhage Cystoid macular edema Retinal detachment.
Grand Rounds Eddie Apenbrinck M.D. University of Louisville School of Medicine Department of Ophthalmology & Visual Sciences 11/07/2014.
M.R.AKHLAGHI MD  It is based on ophthalmoscopic signs.
Retina Conference Janelle Fassbender, MD, PhD University of Louisville Department of Ophthalmology and Visual Sciences 01/23/2014.
Grand Rounds Brooke LW Nesmith, M.D., J.D.
Grand Rounds Niloofar Piri, MD Jan 17th  CC: Blind spots and blurry vision OU for more than 2 years (OS more severely affected)  HPI: A 74-y Caucasian.
Grand Rounds Best Disease Mark Sherman MD University of Louisville Department of Ophthalmology and Visual Sciences 04/04/2014.
Grand Rounds Ethambutol Toxicity Mark Sherman MD University of Louisville Department of Ophthalmology and Visual Sciences 11/21/2014.
Approach to a case of vitreous haemorrhage Sandeep Saxena MS, FRCSEd Professor Department of Ophthalmology KGMU, Lucknow September 27, 2014.
Grand Rounds Shivani V. Reddy, M.D. 7/18/14 University of Louisville Department of Ophthalmology and Visual Sciences.
DIABETES AND EYE DISEASE: LEARNING OBJECTIVES
VR Disorders; Clinical presentation, classification and RD Ayesha S Abdullah
VR Disorders Retinal Detachment (RD)
Diabetic Retinopathy Steven Sanislo, M.D. Assistant Professor Stanford University Department of Ophthalmology.
Idiopathic Perifoveal Telangiectasia Laura S Gilmore, MD Department of Ophthalmology TTUHSC March 12, 2004 Discussant: Kelly T Mitchell, MD.
Clinical Rounds Taylor Strange, D.O. University of Louisville School of Medicine Department of Ophthalmology and Visual Sciences Friday, June 6th 2014.
Retina Conference Eddie Apenbrinck, M.D. University of Louisville
Optic disk edema and macular serous retinal detachment as an early sign of Bartonella henselae systemic infection Dr. Carlos Alvarez-Guzmán 1 Dr. Alejandro.
Grand Rounds Conference Reema Syed, MBBS University of Louisville Department of Ophthalmology and Visual Sciences June 19, 2015.
The Diabetic Retinopathy Clinical Research Network
Grand Rounds Nanophthalmos Mark Sherman MD University of Louisville Department of Ophthalmology and Visual Sciences 2/20/2015.
Grand Rounds Conference Eric Downing MD University of Louisville Department of Ophthalmology and Visual Sciences 11/7/2014.
Diabetic Retinopathy.
1 Macular Morphology and Visual Acuity in the Comparison of Age-related Macular Degeneration Treatments Trial (CATT) Jaffe GJ, Martin DF, Toth CA, Daniel.
European Association for Vision and Eye Research – Crete, Oct 5-8, 2011 Ranibizumab for the Treatment of Exudative Age-Related Macular Degeneration Associated.
Mahmood J Showail 11/03/2009. A 17 -year-old high school female student presented to our clinic with history of sudden decrease of vision in her left.
Josephine-Liezl Cueto, M.D.* Kendall R. Dobbins, M.D.* Geisinger Medical Center, Department of Ophthalmology Danville, PA *No financial interest.
Acute and Chronic visual loss By Dr. ABDULMAJID ALSHEHAH Ophthalmology consultant Anterior Segment and Uveitis consultant.
Diabetes and the Eye Karen B. Saland, M.D. August 18, 2008.
Grand Rounds Amir R. Hajrasouliha, M.D. University of Louisville Department of Ophthalmology and Visual Sciences Thursday, December 5 th, 2014.
Grand Rounds Conference
Canadian Ophthalmological Society Evidence-based Clinical Practice Guidelines for the Management of Glaucoma in the Adult Eye.
Blindness or low vision effects more than 3 million Americans 40 years and older, and this number is projected to reach 5.5 million by In addition.
Siderosis Bulbi Zamzam Al-baker,MD Consultant Opthalmology
Acute Retinal Pigment Epithelitis
Ahmed Y. Hatata, MSc Rowayda M. Amin, MSc Assistant Lecturer Ophthalmology Alexandria University, Egypt Toxocariasis.
Neuroretinitis Anna-Maria Gerlach, Werner Inhoffen Deshka Doycheva, Manfred Zierhut Centre of Ophthalmology University of Tuebigen Germany.
A Case of ?????? ????? MD Associate Prefessor Labbafinejad Medical Center Shahid beheshti University of Medical Sciences Feb 2014.
OPHTHALMOLOGY MACULA DEGENERATION MBChB 4 Prof P Roux 2012.
Posterior Scleritis associated with Orbital Pseudotumor Nikolas London, MD Retina Consultants San Diego.
Manfred Zierhut Manfred Zierhut Centre of Ophthalmology University of Tuebingen, Germany Masquerade Syndrome.
Live intraocular worm causing multifocal choroiditis Dr Mamta Agarwal Dr J Biswas.
Acute choroidal ischemia and Toxoplasmic Retinochoroiditis Acute choroidal ischemia and Toxoplasmic Retinochoroiditis Sonia Attia, MD Imen Ksiaa, MD Moncef.
Endoscopic Management of Displaced IOL Causing Recurrent Hyphema in Patient With Pseudoexfoliation J. M. Rouse, M. A. Khaimi Dean McGee Eye Institute,
Sympathetic Ophthalmitis Annie Mathai, Rajeev K Reddy, Hemant S Trehan, Ritesh Narula Smt.Kanuri Santhamma Retina Vitreous Centre, Kallam Anji Reddy Campus,
Desinee Drakulich O.D.  I have no affiliation, nor do I received financial compensation from any of the companies or brands used in this presentation.
Punctate Inner Choroidopathy Ahmed Magdy Bedda, MD, PhD Professor of Ophthalmology Rowayda M. Amin, MSc Assistant lecturer of Ophthalmology Alexandria.
VR Disorders Common Clinical Presentation & Retinal Detachment (RD)
Grand Rounds Eddie Apenbrinck MD University of Louisville School of Medicine Department of Ophthalmology & Visual Sciences 3/18/16.
BRVO. Present by Sattar Heidari MD General ophthalmologist.
Retina Imaging Conference
Retina Imaging Conference Denis Jusufbegovic, M.D. University of Louisville Department of Ophthalmology and Visual Sciences 2/11/16.
OVD of the retina CRAO Hypertensive retinopathy Ayesha S abdullah
Acute macular edema and peripapillary soft exudate after pancreas transplantation with accelerated progression of diabetic retinopathy  Fang-Yi Tsai,
Macular Epiretinal membrane
가톨릭대학교 의과대학 안과 및 시과학 교실 R3 장동진 / Pf.이원기
Grand Rounds Retinal vascular disease with unique findings
Age Related macular degeneratIon-ClassIfIcatIon
Grand Rounds A Case of Hypertension and Intraocular Hemorrhage
AGE-RELATED MACULAR DEGENERATION (AMD)
To Treat Or Not To Treat…
January 16, 2019.
Multiple evanescent white dot syndrome
Multiple Evanescent White Dot Syndrome (MEWDS)
Presentation transcript:

Grand Rounds Peripheral Exudative Hemorrhagic Chorioretinopathy Mark Sherman MD University of Louisville Department of Ophthalmology and Visual Sciences 08/01/2014

Subjective CC: Decreased vision in the right eye for four months HPI: 70 year old white female presented to the retina clinic with a four month history of painless decreased vision in her right eye. Patient denied any other ocular symptoms. No history of trauma. No recent illness. POH: None PMH: IDDM, HTN

Exam OD OS BCVA: CF @ Face 20/30 Pupils: 53 53 No APD IOP: 14 14 EOM: Full OU

Anterior Segment Exam SLE: OD OS L/L WNL WNL Conjunctiva WNL WNL K WNL WNL AC WNL WNL I/L 2+ NS 2+ NS (No NVI OU)

DFE OD: Dense vitreous hemorrhage, unable to view disc or fundus OS: Disc WNL, attenuated vessels, few scattered microaneurysms (No NVD/NVE)

B-Scan OD Dense vitreous hemorrhage; retina flat

Assessment/Differential Diagnosis Assessment: 70 year old diabetic white female with a dense vitreous hemorrhage OD x ~4 months DDx: 1) Proliferative Diabetic Retinopathy 2) Retinal Tear/Break 3) Exudate age-related macular degeneration Plan: Pars Plana Vitrectomy OD

Surgical Video

1 Week Follow-Up S: Vision markedly improved, no complaints O: BCVA: 20/30 OD, Anterior segment: Unchanged DFE OD: retina flat, ~25% air bubble, large sub-retinal clot inferior to inferior arcade surrounded by laser, peripheral laser 360 degrees A: Peripheral Exudative Hemorrhagic Chorioretinopathy

Peripheral Exudative Hemorrhagic Chorioretinopathy Thought to be a variant of age related macular degeneration Characterized by blood in the subretinal or sub-retinal pigment epithelial space in the peripheral retina More common in older (70-80) Caucasians (~90%) Often confused on presentation for vitreous hemorrhage secondary to retinal detachment or break, choroidal melanoma, or retinal artery macroaneurysm

Peripheral Exudative Hemorrhagic Chorioretinopathy Three characteristic lesion types Hemorrhagic: subretinal or sub-pigment epithelium blood present in the absence of exudate (60%) Exudative: subretinal exudates in the absence of clinically detectable blood (10%) Exudative-Hemorrhagic: both blood and exudates present (30%) Treatment is usually not required unless secondary complications occur (persistent vitreous hemorrhage, retinal detachment, extension into the macula)

Retrospective chart review of 173 eyes (146 patients) Peripheral Exudative Hemorrhagic Chorioretinopathy Simulating Choroidal melanoma in 173 eyes Retrospective chart review of 173 eyes (146 patients) Mean age: 80 145 (99%) Caucasian 98 (67%) Female 171 (99%) were referred for the diagnosis of choroidal melanoma Shields CL, Salazar PF, et al. Peripheral Exudative Hemorrhagic Chorioretinopathy Simulating Choroidal Melanoma in 173 eyes. Ophthalmology. 2009;116:529-35.

Common clinical features: Peripheral Exudative Hemorrhagic Chorioretinopathy Simulating Choroidal melanoma in 173 eyes Common clinical features: Subretinal hemorrhage: 78% Serous RPE detachment: 28% Vitreous hemorrhage: 24% Retinal exudation: 21% Associate macular changes: RPE changes: 23% Drusen: 17% Choroidal neovascularization: 8% Shields CL, Salazar PF, et al. Peripheral Exudative Hemorrhagic Chorioretinopathy Simulating Choroidal Melanoma in 173 eyes. Ophthalmology. 2009;116:529-35.

Features found to differentiate from melanoma: Peripheral Exudative Hemorrhagic Chorioretinopathy Simulating Choroidal melanoma in 173 eyes 15 months of observation 90% stabilized or regressed 10% progressed 7% of patients developed exudative macular changes Features found to differentiate from melanoma: Retinal exudation Hypofluorescence on FA Lack of sentinel vessels Cleft separating clot from from choroid on ultrasound Shields CL, Salazar PF, et al. Peripheral Exudative Hemorrhagic Chorioretinopathy Simulating Choroidal Melanoma in 173 eyes. Ophthalmology. 2009;116:529-35.

Intravitreal Bevacizumab Injection for Peripheral Exudative Hemorrhagic Chorioretinopathy Case report of 74 year female referred for suspicion of choroidal melanoma OD Patient presented with 20/50 vision OD, WNL anterior segment, mild vitreous hemorrhage, and a serous retinal detachment with retinal and subretinal hemorrhages in the inferior periphery B-Scan: 8mm x 3mm infero-temporal lesion Socorro, MA, Sabater N, et al. Intravitreal Bevacizumab Injection for Peripheral Exudative Hemorrhagic Chorioretinopathy. Jpn J Ophthalmol. 2011;55(4)425-7

Intravitreal Bevacizumab Injection for Peripheral Exudative Hemorrhagic Chorioretinopathy Patient was given a diagnosis of peripheral exudative hemorrhagic chorioretinopathy and was observed 2 months later the patient returned with decreased vision (20/100) and complaints of metamorphopsia Exam showed increased vitreous hemorrhage and extension of the serous retinal detachment into the macula Patient was given an intravitreal injection of bevacizumab One week follow-up: vision had improved to 20/40, improvement of vitreous heme and complete resolution of serous detachment Socorro, MA, Sabater N, et al. Intravitreal Bevacizumab Injection for Peripheral Exudative Hemorrhagic Chorioretinopathy. Jpn J Ophthalmol. 2011;55(4)425-7

References Annesley, WH JR: Peripheral exudative hemorrhagic retinopathy. Trans Am Ophthalmol Soc 78:321-364, 1980 BCSC: Retina and Vitreous. Peripheral Retinal Neovascularization. Pgs: 121-22 Mantel I, Uffer S, Zografos. Peripheral Exudative Hemorrhagic Chorioretinopathy: A Clinical, Angiographic, and Histologic Study. Am J Ophthalmol. 2009;148:932-38 Pinarci EY, Kilic, et al. Clinical Characteristics of Peripheral Exudative Chorioretinopathy and its Response to Bevacizumab Therapy. Eye. 2013;27:111-12 Shields CL, Salazar PF, et al. Peripheral Exudative Hemorrhagic Chorioretinopathy Simulating Choroidal Melanoma in 173 eyes. Ophthalmology. 2009;116:529-35. Socorro, MA, Sabater N, et al. Intravitreal Bevacizumab Injection for Peripheral Exudative Hemorrhagic Chorioreintopathy. Jpn J Ophthalmol. 2011;55(4)425-7