Ebola Hemorrhagic Fever Cory Breaux

Ebola Hemorrhagic fever is a disease caused by any of the four virulent strains of the Ebola virus bola_1.jpg

Hemorrhagic fevers are diseases causing excessive bleeding, fever, and frequently death cdn.com/content/image/1- s2.0-S X X- gr1.jpg

Other Hemorrhagic diseases include yellow fever, Dengue fever and Marburg virus /PHIL_2176_lores.jpg

Ebola is a member of the filovirus family, which was first identified in content/14/8/800.long

The natural reservoir is unknown, although some species of bats carry the virus rg/writable/rich_text_editor/im ages/hammer_headed_bat.jpg

The virus particle, recognized by “Shepherd’s crook” shape, contains a single DNA strand ebola.jpg

The first outbreak of Ebola was 1976 in the Democratic Republic of the Congo le/week10d.html

All outbreaks have been in sub-Saharan Africa, and have been small (<318 cases) b/images/ebola/ebolamap.jpg

There have been 3 incidences of exposure in the US, but all have occurred in labs

It is transmitted from animals to humans or human to human via bodily fluids cposters/index.htm

Thus, healthcare workers are at the greatest risk for acquiring the disease cposters/index.htm

Ebola enters the body via mucous membranes, skin abrasions or contaminated needles ml/tileshop_pmc/tileshop_pmc_inline.html?ti tle=Click%20on%20image%20to%20zoom&p= PMC3&id= _DMM000471F1.jpg

Earliest symptoms are flu-like Around day 5, characteristic rash appears g/encyclopedia/graphics/ images/en/17160.jpg

Infection then becomes systemic, leads to apoptosis, hemorrhage, shock and death

There is no treatment available – only containment stops spread

No vaccine currently exists, and the disease is difficult to distinguish early in an outbreak rights.org/assets/images/p anzi-ward.jpg

Lethality makes research difficult in the lab and speed makes it difficult to assess epidemiologically during outbreaks ons/8/8e/Positive-pressure_biosafety_suit.jpg

References Bente, D., J. Gren, J. E. Strong, and H. Feldmann. "Disease Modeling for Ebola and Marburg Viruses." Disease Models and Mechanisms (2009): PubMed. National Institutes of Health. Web. 30 Oct "Ebola Haemorrhagic Fever." World Health Organization, Aug Web. 30 Oct "Ebola Hemorrhagic Fever Information Packet." CDC Special Pathogens Branch - Ebola Hemorrhagic Fever. Centers for Disease Control and Prevention, Web. 30 Oct "Filoviruses." CDC Special Pathogens Branch. Centers for Disease Control and Prevention, n.d. Web. 30 Oct "Interim Guidance for Managing Patients with Suspected Viral Hemorrhagic Fever in U.S. Hospitals." CDC Special Pathogens Branch - Ebola Hemorrhagic Fever. Centers for Disease Control and Prevention, 19 May Web. 30 Oct Rollin, Pierre E. "Viral Hemorrhagic Fevers." CDC Yellow Book Centers for Disease Control and Prevention, 1 July Web. 30 Oct Suzuki, Y., Gojobori, T. “The Origin and Evolution of Ebola and Marburg Viruses.” Mol Biol Evol 14(8) (1997): PubMed. National Institutes of Health. Web. 6 November Zampieri, Carisa A., Nancy J. Sullivan, and Gary J. Nabel. "Immunopathology of Highly Virulent Pathogens: Insights from Ebola Virus." Nature Immunology 8.11 (2007): Academic OneFile. Gale Cengage Learning. Web. 30 Oct