Anthony Catalano
Any device that analyzes a biological compound into a measurable signal Composed of a bioreceptor, transducer, and an electronic peripheral
Bioreceptor: Part of device that interacts with a biological material to identify and interact with a target molecule Transducer: Part of the device that turns the target molecule into a measured signal Electronic Peripheral: Turns the measured signal into a graphical user interface (GUI) utilizing microprocessors Enzymes, Antibodies, or nucleic acids. Piezoelectric, Thermal, Electrochemical, and Optical LED Display
Piezoelectric: crystal detector uses the change of frequency to calculate change in mass Thermal: measures change in heat (exothermic, endothermic) Electrochemical: (Amperometric, or potentiometric) uses electrodes to measure current Optical: uses Surface Plasmon Resonance (SPR), or reflectance to identify various biological molecules Measures Mass Measures heat, requires large sample size, complicated devices Amperometric are among the most common transducers for biosensors Great for identifying antigens, or cancerous cells in a solution
Current Applications Lab-on-a-chip Pollutant Control Patient Diagnosis Detection of harmful pathogens, bacteria, toxic compounds Future Disposable Low Cost Increased Sensitivity Improved Microprocessors Multipurpose Environmental friendly
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