The Story of Human Evolution. Part 1: From ape-like ancestors to modern humans Part 2: What makes us human? Evolution and adaptation in modern humans.

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Presentation transcript:

The Story of Human Evolution

Part 1: From ape-like ancestors to modern humans Part 2: What makes us human? Evolution and adaptation in modern humans

We are all close relatives in our DNA

Modern humans continued to evolve as they encountered new environments, new diseases and new ways of living

Evolution is a gradual change in genetic makeup from one generation to the next Evolution can happen by chance, or by natural selection

How natural selection works 1. Individuals are variable

How natural selection works 2. Some variations are inherited 1. Individuals are variable

How natural selection works 2. Some variations are inherited 3. Individuals with the most favourable variations have more offspring 1. Individuals are variable Favourable variations become more common

Over time, natural selection changes organisms in response to their environment

Evolution in action: Lactose tolerance

Domestication of cattle drove selection for lactose tolerance

Percentage of people with lactose intolerance around the world

Evolution in action: Blue eyes

Blue eyes result from a single genetic change less than 10,000 years ago Blue eyes are not physically advantageous, but may have been more attractive

Percentage of Europeans with light-coloured eyes

Are we still evolving? ?

Modern life has changed but not stopped human evolution

The invention of agriculture and associated dietary and lifestyle changes still drive human evolution today Gene variants involved in dietary changes and disease resistance are continuing to evolve

Disease is an important driver of evolution

Genes that confer resistance to malaria are strongly selected for Malaria is one of the world’s most prevalent and fatal diseases

Allele frequencies of malaria resistance gene FY*O P C Sabeti et al. Science 2006;312: Malaria resistance genes are at high frequency in Africa

The future of human evolution

© Produced by Hilary Miller in association with the Allan Wilson Centre for Molecular Ecology and Evolution Thanks to Azra Moeed, Caroline Thomas, and Glenda Lewis for assistance with preparing this presentation

Image credits Slides 1, 2: TRANZ INTERNATIONAL Image Library Ltd Slide 3: TRANZ INTERNATIONAL Image Library Ltd and iStockphoto Slide 4: Science Photo Library Slide 5: Wikimedia Commons Slides 6-8: Univ. of California Museum of Paleontology ( Slide 9: Moth - Sarah Beach, stock xchng; Gecko - TRANZ INTERNATIONAL Image Library Ltd; Kakapo – Wikimedia Commons Slide 10: Wikimedia Commons Slide 11: Igor Spanholi, stock.xchng Slide 12: Wikimedia Commons Slides 13, 14: TRANZ INTERNATIONAL Image Library Ltd Slide 15: Wikimedia Commons Slide 16: Science Photo Library Slide 17: TRANZ INTERNATIONAL Image Library Ltd Slide 18: Fields – Eva Schuster, stock xchng; Barley – David Thomson, stock xchng; Crowd - TRANZ INTERNATIONAL Image Library Ltd Slide 19, 21: TRANZ INTERNATIONAL Image Library Ltd Slide 22: Science Magazine, American Association for the Advancement of Science Slides 23-25: TRANZ INTERNATIONAL Image Library Ltd