Kidney biopsies at Southampton General Hospital, UK Dr Pankaj Deshpande.

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Presentation transcript:

Kidney biopsies at Southampton General Hospital, UK Dr Pankaj Deshpande

SGH Kidney biopsies between Jan 2001 to Oct children identified 17 boys, 7 girls Age range: 2 years to 16 years

Exclusion criteria Children with nephrotic syndrome who had haematuria Children with HSP who had a kidney biopsy for persistent proteinuria

Demographics

Features 6 children with associated proteinuria (2 nephrotic range) 2 children with renal dysfunction(1 male, 1 female) 2 children with familial haematuria Except for haematuria, no complications of the biopsy

Haematuria

Results 6 children with proteinuria (5 boys, 1 girl) MCGN, 3 Alport’s and 2 IgA 3 children with familial haematuria 2 normal, 1 Alport’s 2 children with renal dysfunction PSAGN

Literature Birmingham Childrens’ Hospital Renal biopsies in 322 children Continuous microscopic / recurrent macroscopic haematuria for > 6 months

Results IgA 78 children (24%) (61/17::M:F) Alport 86 children (27%) (50/36) Thin basement membrane 50 (15%) (18/32) Hilar vasculopathy 28 (9%) (23/5) Miscellaneous 32 (10%) (14/18) Normal 48 (15%) (32/16)