© The Johns Hopkins University and The Johns Hopkins Health System Corporation, 2011 CUSP for VAP: EVAP NHSN VAE Surveillance Definition Review Call in information Phone #: Pass code:

© The Johns Hopkins University and The Johns Hopkins Health System Corporation, 2011 CUSP for VAP: EVAP NHSN VAE Surveillance Definition Review Presented by: Kathleen Speck, MPH September 13, 2012 Armstrong Institute for Patient Safety and Quality

Our Collaborators – Karol G. Wicker, MHS Senior Director, Quality Policy & Advocacy Maryland Hospital Association –Mary Catanzaro RN BSMT CIC Project Manager HAIs Hospital and Healthsystem Association of Pennsylvania 3

Learning Objectives To discuss the NHSN VAE definition. To discuss the linelist generator developed by Dr. Michael Klompas Armstrong Institute for Patient Safety and Quality 4

NHSN Surveillance Assessment must take place for all VAE tiers –VAC - Ventilator-associated Condition –IVAC - Infectious Ventilator-associated Condition –Possible Ventilator-associated Pneumonia –Probable Ventilator-associated Pneumonia Armstrong Institute for Patient Safety and Quality 5

VAC Definition Criteria 8 Patient intubated for > 2 calendar days Baseline stability –Baseline: 2 calendar days immediately preceding the first day of increased daily minimum PEEP or FiO2 requirements –Stability: ≥ 2 calendar days of stable or decreasing daily minimum FiO2 or PEEP requirements Armstrong Institute for Patient Safety and Quality 6

Threshold change for VAC Threshold rise in daily minimum: –PEEP by ≥3 cm H2O or –FiO2 by ≥20 points –sustained ≥2 days Armstrong Institute for Patient Safety and Quality 7

Example - VAC Armstrong Institute for Patient Safety and Quality 8 Stable

Example – no VAC Armstrong Institute for Patient Safety and Quality 9 Unstable

Example – no VAC Armstrong Institute for Patient Safety and Quality 10

Subsequent VAEs VAEs are defined as 14 days –Starts on day 1 of worsening oxygenation –New VAE cannot be reported until 14 day period has elapsed Armstrong Institute for Patient Safety and Quality 11

VAE Outcomes VAE = VAC, IVAC, Possible VAP and Probable VAP VAC = Significant respiratory deterioration after 2 or more days of stability IVAC = VAC + abnormal temp or WBC + ≥ 4 days of new antibiotics Possible VAP = IVAC + purulent sputum or positive sputum/BAL culture Probable VAP = IVAC + purulent sputum AND positive sputum/BAL culture Armstrong Institute for Patient Safety and Quality 12

Setting Up a Linelist Armstrong Institute for Patient Safety and Quality 13

Linelist Definitions Armstrong Institute for Patient Safety and Quality 14

Steps to generate linelist for VAE Begin with “Daily Linelist” Enter daily minimum PEEP and FiO2 for every ventilated patient for every calendar day the patient spends any time on a ventilator Worksheet will automatically flag events that fulfill criteria for VAC If a patient is not identified as having VAC, don’t collect any further information for that patient. Armstrong Institute for Patient Safety and Quality 15

Step 1 – VAC Armstrong Institute for Patient Safety and Quality 16

Determination of IVAC Patients where VAC has already been determined Enter: –Tmin and Tmax –WBCmin and WBCmax –QAD – Qualifying antibiotic day IVAC requires 4 contiguous days of a new antibiotic starting within the 5 days starting 2 days before the onset Armstrong Institute for Patient Safety and Quality 17

Step 2 - IVAC Armstrong Institute for Patient Safety and Quality 18

New Antimicrobial Agent Qualifying Antimicrobial Day (QAD) Any agent listed in the Appendix of the Device Associated Events: VAE (pages through 10-21) that: –Is initiated on or after the third day of mechanical ventilation AND –is started in the 5 day period defined by 2 days before the day of the event the 2 days after AND –Was not given to the patient on either of the two days preceding the current event Armstrong Institute for Patient Safety and Quality 19

Qualifying Antibiotic Days - Timing (VAC has already been established) Armstrong Institute for Patient Safety and Quality 20

Example Antibiotic Worksheet Armstrong Institute for Patient Safety and Quality 21

Determination of Possible VAP or Probable VAP Patients where IVAC has been determined From Sputum of BAL gram stain –Enter Polys – polys, neutrophils or WBC (semiquantitative scale) Epis – epithelial cells or squamous cells (semiquantitative scale) Culture – result Quantity - threshold (10^5 for endotracheal aspirate, 10^4 for BAL, 10^3 for protected specimen brush). Semi-quantitative equivalent also acceptable. Answer Yes or No. Armstrong Institute for Patient Safety and Quality 22

Step 3 – Possible VAP or Probable VAP Armstrong Institute for Patient Safety and Quality 23

Questions? Armstrong Institute for Patient Safety and Quality 24