SUPERFICIAL FUNGAL INFECTION DERMATOPHYTOSIS THREE GENERA KNOWN TO CAUSE DISEASE -TRICOPHYTON - MICROSPORUM - EPIDERMOPHYTON

EPIDEMIOLOGY GEOPHILIC - – M.GYPSEUM – M. FERRUGINEUM - T. TERRESTRE - T.VIOLACEUMGEOPHILIC - – M.GYPSEUM – M. FERRUGINEUM - T. TERRESTRE - T.VIOLACEUM ZOOPHILIC - - M. CANIS – CAT, DOGS,SHEEPS - T. EQUINUM – CATS, DOGS,CATTLES - T. VERRUCOSUM – CATS, DOGS, CATTLES,SHEEPSZOOPHILIC - - M. CANIS – CAT, DOGS,SHEEPS - T. EQUINUM – CATS, DOGS,CATTLES - T. VERRUCOSUM – CATS, DOGS, CATTLES,SHEEPS ANTHROPOPHILIC - - E. FLOCCOSUM –M. AUDOUINII –T. MENTAGROPHYTES –T. RUBRUM – T. TONSURANS –ANTHROPOPHILIC - - E. FLOCCOSUM –M. AUDOUINII –T. MENTAGROPHYTES –T. RUBRUM – T. TONSURANS –

PATHOGENESIS FUNGI MUST OVER COME - EFFECT OF UV LIGHT –TEMPERATURE VARIATION – COMPITION WITH NORMAL FLORA -FUNGISTATIC AGENTS – FATTY ACIDS,SPHINGOSINES - EPIDERMAL GROWTH DTH IMMUNE RESPONSE

TINEA CAPITIS ECTOTHRIXENDOTHRIX YELLOW- GREEN FLUORESCENCEDULL GRAY-GREEN FLUORESCENCE M.AUDOUINII M.CANIS M.FERRUGINEUM T.SCHOENLEINII NO FLUORESCENCE M.GYPSEUM T.MENTAGROPHYTES T. RUBRUM T.TONSRANS T. VIOLACEUM

ORGANISMS ASSOCIATED WITH CLINICAL TYPES OF TINEA CAPITIS INFLAMMATORY ZOOPHILIC GEOPHILIC NONINFLAMMATORY ANTHROPOPHLIC ECTOTHRIC BLAK DOT ANTHROPOPHILIC ENDOTHRIX FAVUS M.AUDOUINII M. CANIS M. GYPSEUM T.MENTAGROPHYTE T.TONSURANS T. VERRUCOSUM M.AUDOUINII M. CANIS M.FERRUGINEUM T.TONSURANS T.VIOLACEUM M.GYPSEUM T. SCHOENLEINII T.VIOLACEUM

TINEA CAPITIS

BLACK DOT TINEA CAPITIS

INFLAMMATORY T. CAPITIS

TINEA BARBAE INFAMATORY TYPE- T. MENTAGROPHTE, T. VERRUCOSUM SUPERFICIAL TYPE - ANTHROPOPHILIC –T. VIOLACEUM,T.RUBRUM CIRCINATE TYPE

TINEA BARBAE

TINEA FACEII

TINEA BARBE

TYPICAL TINEA CORPORIS

TINEA CORPORIS

INFLAMMATORY T. CORPORIS

TINEA CORPORIS

TINEA UNGUIUM

TINEA MANUM

TINEA CRURIS

TINEA PEDIS CHRONIC INTERTRIGINOUS TYPE CHRONIC HYPERKERATOTIC TYPE VESICULOBULLOUS TYPE ACUTE ULCERATIVE TYPE

TINEA PEDIS

KOH MOUNT

ENDOTHRIX FUNGUS

ECTOTHRIX FUNGUS 100X

TREATMENT SYSTEMIC THERAPY TOPICAL THREAPY **

SYSTEMIC ANTIFUNGALS ALLYLAMINS – INHIBITS SQUALENE EPOXIDASE BLOCKING BIOSYNTHESIS OF ERGOSTEROL FUNGICIDAL 3 TO 6 mg/kg OD CONTRAINDICATED IN PREGNANCY & LACTATION TRIAZOLES – ITRACONAZOLE, FLUCONAZOLE INHIBIT 14 alfa DEMETHYLASE ENZYME IN CELL MEMBRANE USEFUL FOR CONVERSION OF SQUALENE TO ERGOSTEROL. IMIDAZOLE – KETOCONAZOLE GRISEOFULVIN – DISRUPS MICROTUBULE MITOTIC SPINDLE FORMATON THUS ARREST MITOTIC AT METAPHASE STAGE

TREATMENT TOPICAL -ALLYLAMINES – TERBINAFINE,NAFTIFINE -BENZYLAMINE - BUTENAFINE -IMIDAZOLES CLOTRIMAZOLE, MICONAZOLE, KETOCONAZOLE -TOLNAFTAE

THANK YOU….,