Vaccine Technology. Newer Technology for Dosing:

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Presentation transcript:

Vaccine Technology

Newer Technology for Dosing:

Vaccine Technology New Target Groups:

Old Technology: –Grow in animals (vaccinia in calves for smallpox; rabbit brains for rabies) –Simple bacterial culture (Cholera vibrio) then inactivation –Grow in eggs (influenza, vaccinia) then inactivate >100 million eggs used for influenza in the USA every year Vaccine Technology

Newer Technology: –Mammalian cell culture: live and killed vaccines –Subunit vaccines: From serum (HBV) or virus / bacterial disruption Made via recombinant DNA technology –Recombinant vaccine vectors –DNA vaccines

Vaccine Technology

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