Past, Present and the Future Rabin Mohanty Consultant Paediatrician Blackpool.

Slides:



Advertisements
Similar presentations
Stem Cells and Diabetes
Advertisements

Children Aged 5 to
Dr. Hemant Gupta [Associate Prof. & Unit Head, Dept of Medicine, J. J
Basics of Organ Transplantation Lon Eskind, MD Director Liver Transplant, CMC Assoc. Medical Director of LifeShare.
CF Related Diabetes ADEU November Cystic Fibrosis Genetic disorder Exocrine pancreas dysfunction Autosomal recessive inheritance Several identified.
Diabetes Are you at risk?.
DR LUCY MUNGAI, LECTURER DEPARTMENT OF PAEDIATRICS AND CHILD HEALTH, UNIVERSITY OF NAIROBI. CHALLENGES IN THE MANAGEMENT OF CHILDHOOD DIABETES IN KENYA.
Diabetes Nhung H. Nguyen. Definition: “A metabolic disease in which the body’s inability to produce any or enough insulin causes elevated levels of glucose.
Insulin Pump What to tell your patient!! Prakash Abraham Isla Fairley.
Vesicle Transport Chapter 13. Multivesicular bodies form on the pathway to late endosomes.
Stem Cells and Diabetes The Present. Background Diabetes affects more people and causes more deaths each year than breast cancer and AIDS combined. The.
From Stem Cells to Beta Cells: Possible Cure for Diabetes Mellitus By Ryan Scavinski.
Richard Croft Diabetes Lead Berkshire West. The impact of a 1% reduction in HbA1c.
12.4 Diabetes and its Control. Learning Objectives Learn the two types of diabetes and how they differ. Learn how each type of diabetes can be controlled.
 Research Topic Type 1 Diabetes by Sonia Donaires.
Turning TypeOne to The Plan for a World without T1D.
Organs for research and education Matthew Bock. When are organs used for research? Only after they have been determined unsuitable for transplant.
By: Alicia Myall.  Also known as “insulin dependant diabetes” or “juvenile onset diabetes”  Life long illness  Most likely to be diagnosed in children,
ResourcesChapter menu Copyright © by Holt, Rinehart and Winston. All rights reserved. Objectives Describe how lifestyle can lead to diseases. List four.
diasoce3.ppt1 Why is the current therapy not perfect?  Even slightly elevated blood glucose is harmful.  The limiting factor of insulin treatment.
Care for School Children With Diabetes Senate Bill 911/G.S. 115C-47.
GENE THERAPY FOR DIABETES Lindsey Rowbotham Period 7.
Abu Ahmed Consultant Physician Blackpool Victoria Hospital Diabetes Public Lecture.
Medicine. By inserting a gene for human insulin into an E.Coli bacterium, the E. coli will make lots of insulin, which scientists and doctors can collect.
Diabetes: Glucose Monitoring
Stem Cell Research By: Jarrit Locke. The Benefits of Stem Cells  Curing diseases  Repairing damaged organs  Healing burns and scars  Advancements.
Diabetes
Turning TypeOne to The Plan for a World without T1D JDRF Translational Development: Partnering for Success.
Welcome to TypeOneNation The Plan for a World without T1D Presented by: Carol Oxenreiter Saturday, May 31, 2014.
Diabetes Past Present and Future Rich Hartmann 5/11/2010.
Benefits of Biomedical Research. What contributions has biomedical research had to human health?  Treatment for heart disease: ~ The heart- lung machine.
Bradford Insulin Pump Service Gill Atherton Sandra Dudding Diabetes Specialist Nurses.
8.2 Hormones that Affect Blood Sugar. Review What is the Endocrine System? What are the two types of hormones? How do they differ in terms of hormone-
1 Transforming JDRF Research. Impacting Lives. Julia L. Greenstein, PhD AVP Cure Therapies April 10, 2012.
Insulin Delivery: Pumps and Glucose Anna Zhu BME /18/04.
Pediatric Endocrinology Use of Biologic and Chemotherapeutic Agents Pediatric Endocrinology Use of Biologic and Chemotherapeutic Agents.
The Diabetes Tide John Doig. 228, ,154.
Pancreas – Disorders Biology Pancreas The pancreas is between the kidneys and the duodenum and provides digestive juices and endocrine functions.
D IABETES By: Cait O’Neill. Diabetes occurs when there is too much sugar, or glucose, in the blood. Insulin moves sugar from the blood stream to cells.
The genetic bases BY Casey Jaroche
Diabetes: What’s New? What’s Next? Robert P. Hoffman, M.D. Grand Rounds June 1, 2007.
Scottish Neonatal and Paediatric Pharmacists Group PRESCRIBING IN PAEDIATRIC CYSTIC FIBROSIS.
Continuous Glucose Monitors
The University of Georgia Cooperative Extension Definition Group of diseases marked by high blood glucose (blood sugar) levels Caused by defects in Insulin.
Endocrine and Metabolic Disorders Lectures 8 I.Kuziv, MD, PhD.
“Diabetes is not curable, but, fortunately, it is treatable.”
Course: Medical Biotechnology.  Metabolic and Multifactorial disease develops mostly due to deficiency of insulin. As a result high blood sugar will.
STS ISSUES AND THE ENDOCRINE SYSTEM. scientists are taking advantage of the far reaching effects of hormones by genetically and artificially producing.
Maddie Cooper
Diabetes. PANCREAS Regulates blood sugar levels and glucose metabolism Secretes 2 hormones Insulin-allows blood sugar (glucose) to be taken out of the.
Less Until None: A Plan for a World without T1D. 2 LESSUNTILNONE 2 JDRF’s Vision for the Future.
ARTIFICIAL BETA-CELLS AND BETATROPHIN FOR DIABETICS
Antonella Gilmour, NP-PHC November 13, Statistics Site #1Site #2 Total # of patients Total # of patients with diabetes Total #
Diabetes By Amanda Dillen. Diabetes Diabetes Nelitus is a disease that results when the pancreas (an endocrine gland) is incapable of synthesizing enough.
 Indicate how frequently you engage in each of the following behaviors (1 = never; 2 = occasionally; 3 = most of the time; 4 = all of the time) 1.I eat.
“Diabetes” When blood sugar is out of control. What happens if the body can’t handle carbs normally? One result is diabetes. This can be detected by a.
Diabetes and Stem Cells. Diabetes Year 2000 – Estimated 171 million people Year 2013 – Estimated 343 million people Class as an epidemic.
高分子生物材料 人工器官 张国庆
Dr Zaranyika MBChB(Hons) UZ, MPH, FCP SA Department of Medicine UZ-CHS
Diabetes University of Houston – Downtown By: Marlene Trevino Biology 1310 M/W Professor: David Lang.
ResourcesChapter menu Copyright © by Holt, Rinehart and Winston. All rights reserved. Lifestyle Diseases Chapter 14.
Moshe Phillip, M.D., Tadej Battelino, M.D., Eran Atlas, M.Sc., Olga Kordonouri, M.D., Natasa Bratina, M.D., Shahar Miller, B.Sc., Torben Biester, M.D.,
Research in T1D Cumming School of Medicine Department of Paediatrics
Program Goals. Inhaled Insulin: Overcoming Past Obstacles With Advances in Understanding.
Regulating the Cell Cycle
Insulin Use in Primary Care: Practice Challenges
Advancements in Glucose Monitoring
Jennifer McVean, MD September 23, 2010
Scenario 2.
Presentation transcript:

Past, Present and the Future Rabin Mohanty Consultant Paediatrician Blackpool

Before Insulin Before insulin was discovered in 1921, everyone with type 1 diabetes died within weeks to years of its onset JL on 12/15/22 and 2 mos later

Impact Of Insulin On Life Expectancy By The 1940’s Age at start of diabetes Avg. age of death in Avg. age of death in Years Gained82634

Manufactured insulin, 'Iletin', United States, 1923

Newer insulin pens

1st generation of insulin pumps 1960s

Modern Insulin Pump

Tandem’s t:slim insulin pump

What is an Artificial Pancreas?

Islet Cell Transplantation

Is Diabetes Curable?  Implantable Insulin Pumps  Islet Cell Transplant  Gene Therapy  Stem Cell  Vaccine  Newer Drugs

Blackpool Paediatric Diabetes Service  140 children  4 children on insulin pumps( 2 moved)  4 new children on pumps soon  CGMS monitoring  50% on Basal Bolus  HbA1c falling  Less complications